2 products were found matching "Cay14491-25"!
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NB-598
Item number: Cay14912-5
NB-598 is an inhibitor of squalene epoxidase (IC50s = 2 and 0.75 nM for dog liver and human microsomal enzymes, respectively). It selectively inhibits cholesterol synthesis over free fatty acid, triglyceride, and phospholipid synthesis in HepG2 cells at 1 µM. NB-598 (10 mg/kg per day) reduces serum cholesterol...
| Keywords: | 3-([3,3'-bithiophen]-5-ylmethoxy)-N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-ethyl-benzenemethanamine |
| Application: | Squalene epoxidase inhibitor |
| CAS | 131060-14-5 |
| MW: | 449.7 D |
From 35.00€
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AZD 7762
Item number: Cay11491-25
Actively proliferating cells experience blocks at certain checkpoints in the cell cycle when DNA damage is detected. These checkpoints allow for DNA damage repair before further cell cycle progression. Targeting signaling pathways to selectively inhibit repair at these checkpoints in tumor cells is of considerable...
| Keywords: | 3-[(aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-thiophenecarboxamide |
| Application: | Checkpoint kinase (Chk) inhibitor |
| CAS | 860352-01-8 |
| MW: | 362.4 D |
From 34.00€
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