- Search results for Cay14491
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6 products were found matching "Cay14491"!
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Item number: Cay14491-100
The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain. These domains function in linking protein complexes to acetylated nucleosomes, thereby controlling chromatin...
Keywords: | Bromodomain containing protein 7, Protein CELTIX-1 |
Application: | Binding studies |
Expressed in: | E.coli |
Origin: | human |
MW: | 42,2 kD |
642.00€
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Item number: Cay11499-1
Obatoclax is an antagonist of Bcl-2 family members containing four Bcl-2 homology domains, including Bcl-2, Bcl-W, Bcl-xL, and Mcl-1 (Kd = ~500 nM). It prevents the interaction of these pro-survival proteins with Bax or Bak, thereby inducing apoptosis with up-regulation of Bim, induced cytochrome c release, and...
Keywords: | GX15-070, 2-[2-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-3-methoxy-2H-pyrrol-5-yl]-1H-indole, monomethanesulfonate |
Application: | Antagonist of Bcl-2 family members containing four Bcl-2 homology domains |
CAS | 803712-79-0 |
MW: | 413.5 D |
From 84.00€
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Item number: Cay14991-5
Ac-LETD-AFC is a fluorogenic substrate that can be cleaved specifically by caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.Formal Name:...
Keywords: | Caspase-8 Substrate (Fluorogenic), N-Acetyl-Leu-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin,... |
Application: | Fluorogenic Caspase-8 substrate |
CAS | 210345-02-1 |
MW: | 729.7 D |
From 85.00€
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Item number: Cay11491-25
Actively proliferating cells experience blocks at certain checkpoints in the cell cycle when DNA damage is detected. These checkpoints allow for DNA damage repair before further cell cycle progression. Targeting signaling pathways to selectively inhibit repair at these checkpoints in tumor cells is of considerable...
Keywords: | 3-[(aminocarbonyl)amino]-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-2-thiophenecarboxamide |
Application: | Checkpoint kinase (Chk) inhibitor |
CAS | 860352-01-8 |
MW: | 362.4 D |
From 34.00€
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Item number: Cay14496-1
N-Phenylacetyl-L-prolylglycine ethyl ester is a synthetic dipeptide that has been shown to produce positive nootropic and cognitive effects in animal models (0.01-0.8 mg/kg) by a mechanism similar to other related racetam compounds. It can rescue neuroblastoma SH-SY5Y cells from amyloid-induced cytotoxicity,...
Keywords: | GVS-111, Noopept, SGS 111, 1-(2-phenylacetyl)-L-prolyl-glycine, ethyl ester |
Application: | Analytical reference standard, Synthetic dipeptide, Nootropic, Antioxidant, Antiinflammatory |
CAS | 157115-85-0 |
MW: | 318.4 D |
From 84.00€
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Item number: Cay14409-1
Amiloride is a potassium-sparing diuretic. It is an inhibitor of the epithelial sodium channel (ENaC, K0.5 = 2.6 µM for recombinant deltaENaC expressed in X. laevis oocytes). It inhibits sodium transport from bovine kidney cortex membrane vesicles with an IC50 value of 0.4 µM. Amiloride inhibits the urokinase-type...
Keywords: | MK-870, 3,5-diamino-N-(aminoiminomethyl)-6-chloro-2-pyrazinecarboxamide, monohydrochloride hydrate |
Application: | Metabolic studies |
MW: | 266.1 D |
From 54.00€
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