- Search results for Cay11052-25
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9 products were found matching "Cay11052-25"!
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Item number: Cay10522-5
Thapsigargin is an inhibitor of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase (SERCA, IC50 = ~30 nM for the rat liver microsomal enzyme), an ER stress inducer, and a sesquiterpene lactone that has been found in Thapsia. It increases intracellular calcium levels in isolated rat hepatocytes (EC50 = ~80 nM) and...
Keywords: | (3S,3aS,4R,6R,7S,8R)-6-acetoxy-4-(butyryloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-(((Z)-2-methylbut-2-enoyl)oxy)-2-oxo-2,3,3a... |
Application: | SERCA inhibitor |
CAS | 67526-95-8 |
MW: | 650.8 D |
From 94.00€
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Item number: Cay11052-100
Bromodomain-containing protein 4 (BRD4) is a member of the bromodomain and extra-terminal domain (BET) family. It is a ubiquitously expressed nuclear protein with roles in a variety of cellular processes, including regulation of gene transcription, cell cycle progression, and viral genome segregation. BRD4 is...
Keywords: | BRD4, HUNK1, Protein HUNK1, Protein HUNK1, Bromodomain-containing protein 4, Bromodomain-containing protein 4 |
Application: | Binding studies |
MW: | 73,4 kD |
488.00€
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Item number: Cay15225-250
Z-L-Phe-CMK is an inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV) main protease (Mpro), also known as 3C-like protease (3CLpro, Ki = 306 nM). It is selective for SARS-CoV Mpro over calpain, trypsin, and thrombin (Kis = 10, >100, and >100 µM, respectively). Z-L-Phe-CMK (20 µM) also inhibits the...
Keywords: | NSC 251810, N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-carbamic acid, phenylmethyl ester |
Application: | Gemcitabine prodrug, apoptosis inducer |
CAS | 26049-94-5 |
MW: | 331.8 D |
From 50.00€
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Item number: Cay11055-1
ethyl 2-(3-hydroxyphenyl)-4-methylthiazole-5-Carboxylate is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 2-(3-hydroxyphenyl)4-methyl-5-thiazolecarboxylic acid, ethyl ester. CAS Number: 209538-87-4. Molecular Formula: C13H13NO3S. Formula Weight: 263.3. Purity: >97%. Formulation: (Request...
Keywords: | 2-(3-hydroxyphenyl)4-methyl-5-thiazolecarboxylic acid, ethyl ester |
Application: | Synthetic Intermediate |
CAS | 209538-87-4 |
MW: | 263.3 D |
From 105.00€
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Item number: Cay10012562-5
Stearoyl-CoA desaturase (SCD) catalyzes the committed step of the conversion of saturated, long-chain fatty acids to monounsaturated fatty acids. The SCD1 gene is thought to play a key role in lipid homeostasis and body weight regulation. Thus, modulating SCD1 activity pharmacologically may be a useful tool for...
Keywords: | 3-[4-(2-chloro-5-fluorophenoxy)-1-piperidinyl]-6-(5-methyl-1,3,4-oxadiazol-2-yl)-pyridazine |
Application: | SCD inhibitor |
CAS | 944808-88-2 |
MW: | 389.8 D |
From 106.00€
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Item number: Cay10012592-5
Lacosamide selectively enhances sodium channel slow inactivation without affecting fast inactivation. It is effective in multiple rodent models of seizure activity. The neuroprotective effects of lacosamide are also attributed to its ability to modulate collapsin response mediator protein 2 (CRMP-2), a member of the...
Keywords: | ADD 243037, SPM 927, 2R-(acetylamino)-3-methoxy-N-(phenylmethyl)-propanamide |
Application: | Sodium channel modulator |
CAS | 175481-36-4 |
MW: | 250.3 D |
From 66.00€
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Lipid-based Drug Delivery Tools
Item number: Cay15102-250
1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (1,2-POPC) is a phospholipid containing 16:0 and 18:1 fatty acids at the sn-1 and sn-2 positions, respectively. It belongs to a class of phospholipids that are a major component of biological membranes. This compound can be used for liposome production in order to study the...
Keywords: | 1,2-POPC, 1-Palmitoyl-2-Oleoyl-sn-glycero-3-Phosphocholine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylcholine |
Application: | Liposome production |
CAS | 26853-31-6 |
MW: | 760.1 D |
From 102.00€
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Item number: Cay11095-25
Palmitoyl-DL-carnitine is a long-chain acylcarnitine with both intracellular and extracellular roles. Within the cell, palmitoylcarnitine is transported into mitochondria to deliver palmitate for fatty acid oxidation and energy production. Exogenously added Palmitoyl-DL-carnitine alters calcium mobilization in many...
Keywords: | DL-Palmitoylcarnitine, DL-Hexadecanoylcarnitine, Hexadecanoyl-DL-carnitine, NSC 628323,... |
Application: | Lipid studies |
CAS | 6865-14-1 |
MW: | 436.1 D |
From 35.00€
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Item number: Cay11225-50
2,3-Dimethylmethcathinone (hydrochloride) is a potential designer drug with combined features of amphetamines, cathinones, and phenethylamines. It is structurally related to 4-methylmethcathinone, (Cay-10801), a psychoactive compound that has been identified in products sold as bath salts and plant food. The...
Keywords: | 2,3-DMMC, 1-(2,3-dimethylphenyl)-2-(methylamino)propan-1-one, monohydrochloride |
Application: | Analytical reference standard, Potential designer drug (structurally related to 4-MMC) |
CAS | 1797981-99-7 |
MW: | 227.7 D |
From 266.00€
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