- Search results for Cay11720
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8 products were found matching "Cay11720"!
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Item number: Cay11720-100
Bromodomain-containing protein 4 (BRD4) is a member of the bromodomain and extra-terminal domain (BET) family. It is a ubiquitously expressed nuclear protein with roles in a variety of cellular processes, including regulation of gene transcription, cell cycle progression, and viral genome segregation. BRD4 is...
Keywords: | BRD4, HUNK1, Protein HUNK1, Protein HUNK1, Bromodomain-containing protein 4, Bromodomain-containing protein 4 |
Application: | Histone studies, Inhibitor screening |
Expressed in: | E.coli |
MW: | 16.6 kD |
488.00€
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Item number: Cay17200-50
AB-FUBINACA (Cay-14039) is an indazole-based synthetic cannabinoid (CB) with 10-fold greater affinity for the CB1 receptor (Ki = 0.9 nM) than that of JWH 018 (Cay-10900). APP-FUBINACA is an analog of AB-FUBINACA in which an isopropyl group has been replaced with a phenylmethyl moiety. The physiological and...
Keywords: | N-[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]-1-[(4-fluorophenyl)methyl]-1H-indazole-3-carboxamide |
Application: | Analytical reference material, Synthetic indazole-based cannabinoid analog (AB-FUBINACA analog) |
CAS | 1185282-03-4 |
MW: | 416.5 D |
From 291.00€
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Item number: Cay11727-50
Ionotropic GABAA receptors are ligand-gated ion channels that facilitate the passing of chloride ions across the cell membrane and promote an inhibitory influence on target neurons. These receptors are the major targets for benzodiazepines and related anxiolytic drugs. Bicuculline is a competitive GABAA receptor...
Keywords: | NSC 32192, 6-[(5S)-5,6,7,8-tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-(6R)-furo[3,4-e]-1,3-benzodioxol-8(6H)-one |
Application: | GABAA receptor antagonist |
CAS | 485-49-4 |
MW: | 367.4 D |
From 60.00€
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Item number: Cay11729-10
1-Naphthyl 3,5-dinitrobenzoate has been identified as a dual 5-lipoxygenase and microsomal prostaglandin E synthase-1 inhibitor with IC50 values of 1 and 3.6 µM, respectively. The scaffold of this compound is being explored for anti-inflammatory drug design.Formal Name: 1-(3,5-dinitrobenzoate) 1-naphthalenol. CAS...
Keywords: | 1-(3,5-Dinitrobenzoyloxy)naphthalene, 1-Naphthalonol 3,5-dinitrobenzoate, 1-(3,5-dinitrobenzoate) 1-naphthalenol |
Application: | Dual 5-lipoxygenase & microsomal prostaglandin E synthase-1 inhibitor |
CAS | 93261-39-3 |
MW: | 338.3 D |
From 43.00€
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Item number: Cay11723-10
Jervine is a naturally occurring teratogenic alkaloid that inhibits the sonic hedgehog pathway (IC50s = 500-700 nM) in vitro. It induces a variety of birth defects in vivo, including holoprosencephaly, cyclopia, cebocephaly, exencephaly, and microphthalmia in rat, chicken, and sheep. Jervine also reduces lipid...
Keywords: | NSC 23898, NSC 7520,... |
Application: | Sonic hedgehog pathway inhibitor, Birth defect inducer |
CAS | 469-59-0 |
MW: | 425.6 D |
From 43.00€
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Item number: Cay11725-10
Platycodin D is a saponin isolated from the root of P. grandiflorum. Root preparations have been used extensively in Chinese herbal medicine for many applications, particularly for upper respiratory disorders and inflammation. The cellular and physiological actions of purified platycodin D have not been...
Keywords: | 3beta-(beta-D-glucopyranosyloxy)-2beta,16alpha,23,24-tetrahydroxy-O-D-apio-beta-D-furanosyl-(1->3)-O-beta-D-xylopyranosyl-... |
Application: | Saponin, Chinese medicinal herb isolate |
CAS | 58479-68-8 |
MW: | 1225.3 D |
From 43.00€
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Item number: Cay11724-10
The hedgehog (Hh) signaling pathway, which is blocked by cyclopamine (Cay-11321), plays a key role in morphogenesis and has potential applications in the treatment of cancer. Veratramine, a teratogenic steroidal alkaloid isolated from the corn lily (Veratrum sp.), is an analog of cyclopamine that can inhibit the Hh...
Keywords: | NSC 17821, NSC 23880,... |
Application: | Signal transduction studies |
CAS | 60-70-8 |
MW: | 409.6 D |
From 84.00€
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Item number: Cay11722-10
Cycloastragenol, the aglycone derivative of astragaloside A (Cay-16677), can be found in various species of Astragalus and is reported to activate telomerase. It has been shown to slow telomere loss, increase replicative capacity, and improve immune function in CD8+ T lymphocytes from HIV-1-infected patients.Formal...
Keywords: | Astramembrangenin, Cyclogalegigenin, 20,24R-epoxy-9,19-cyclolanostane-3beta,6alpha,16beta,25-tetrol |
Application: | Reported telomerase activator |
CAS | 84605-18-5 |
MW: | 490.7 D |
From 43.00€
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