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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay14658-100 | 100 µg | - |
6 - 10 business days* |
465.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Bromodomain-containing protein 3 (BRD3) is a member of the bromodomain and extra-terminal domain... more
Product information "BRD3 bromodomain 2 (human, recombinant)"
Bromodomain-containing protein 3 (BRD3) is a member of the bromodomain and extra-terminal domain (BET) family. It is composed of two N-terminal bromodomains (BD1 and BD2) that bind acetylated lysine on histones, serving to couple histone acetylation marks to the transcriptional regulation of target promoters, and an extra-terminal domain that mediates chromatin interactions. BRD3 is ubiquitously expressed and localizes to the nucleus where it preferentially binds acetylated histone H4 lysine 5 (H4K5), H4K12, and H4K14 at active transcription sites. Knockdown of Brd3 enhances differentiation of C2C12 skeletal muscle myoblasts. Chromosomal translocations leading to the fusion of BRD3 with the nuclear protein in testis (NUT) gene and resulting in expression of BRD3-NUT fusion proteins are associated with NUT midline carcinoma (NMC). Cayman's BRD3 bromodomain 2 protein can be used for Western blot (WB).Synonyms: Bromodomain containing protein 3, ORFX, RING3L, RING3-like protein. Purity: >95% estimated by SDS-PAGE. Source: Recombinant human N-terminal GST-tagged BRD3 bromodomain 2 expressed in E. coli. Amino Acids: 306-416. MW: 40.7 kDa. Formulation: (Request formulation change), 50 mM Tris, pH 7.5, containing 150 mM sodium chloride and 20% glycerol. UniProt Accession #: Q15059.
Keywords: | BRD3, KIAA0043, RING3-like protein, RING3-like protein, Bromodomain-containing protein 3, Bromodomain-containing protein 3 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 14658 |
Properties
Application: | Binding studies |
Conjugate: | No |
Host: | E.coli |
MW: | 40,7 kD |
Purity: | >95% estimated by SDS-PAGE |
Format: | Solution |
Database Information
KEGG ID : | K11721 | Matching products |
UniProt ID : | Q15059 | Matching products |
Gene ID | GeneID 8019 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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