11 products were found matching "Cay11285-50"!

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CI-1040
CI-1040

Item number: Cay11580-50

The dual specific threonine/tyrosine kinase, map kinase kinase (MEK), is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. CI-1040 is a benzhydroxamate compound that potently inhibits MEK in an in vitro mitogen-activated protein kinase cascade assay with an IC50...
Keywords: PD 184352, 2-[(2-chloro-4-iodophenyl)amino]-N-(cyclopropylmethoxy)-3,4-difluoro-benzamide
CAS 212631-79-3
MW: 478.7 D
From 109.00€ *
Review
Delta12-Prostaglandin J2
Delta12-Prostaglandin J2

Item number: Cay18550-500

Delta12-Prostaglandin J2 (Delta12-PGJ2) is a decomposition product of PGD2 in aqueous media in the presence of albumin. It has antitumor and antiviral activity, inhibiting growth of cultured L1210 cells at with an IC50 value of 0.7 µg/ml. Delta12-PGJ2 is present in normal human urine with a 24 hour excretion rate of...
Keywords: Delta12-PGJ2, 11-oxo-15S-hydroxy-prosta-5Z,9,12E-trien-1-oic acid
Application: Bioactive lipid assays
CAS 87893-54-7
MW: 334.5 D
From 54.00€ *
Review
Tazobactam (sodium salt)
Tazobactam (sodium salt)

Item number: Cay17185-250

Tazobactam is a beta-lactamase inhibitor with greater activity against Ambler class A serine penicillinases and class C cephalosporinases, including TEM-1, SHV-1, and P99 (IC50s = 97, 150, and 8.5 nM) than class B metallo-beta-lactamases and the class D oxacillinase OXA-1 (IC50s = 400,000 and 1,400 nM,...
Keywords: CL-307579, YTR 830, 4,4-dioxide...
Application: Antibiotic, beta-lactamase inhibitor
CAS 89785-84-2
MW: 322.3 D
From 43.00€ *
Review
17(S)-HpDHA
17(S)-HpDHA

Item number: Cay13185-250

17(S)-HpDHA is a mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, human glial cells, and mouse brain. 17(S)-HpDHA is generally reduced to 17(S)-HDHA (Cay-10009799), a compound that serves as a precursor to 17(S)-resolvins. 17(S)-HDHA has been shown to inhibit TNF-alpha-induced...
Keywords: 17(S)-HpDoHE, 17(S)-hydroperoxy Docosahexaenoic Acid, 17S-hydroperoxy-4E,7Z,10Z,13Z,15Z,19Z-docosahexaenoic acid
Application: Bioactive lipid assays
CAS 123673-33-6
MW: 360.5 D
From 173.00€ *
Review
Rabbit Anti-HA IgG: DyLight(R) 488, 100 µg
Rabbit Anti-HA IgG: DyLight(R) 488, 100 µg

Item number: Cay11250-1

Rabbit Anti-HA (Hemagglutinin) IgG conjugated to DyLight(R) 488 Antibody:Rabbit polyclonal Anti-HA (YPYDVPDYA) IgG Dye: DyLight(R) 488 Excitation max. lambda: 493 nm Emission max. lambda: 518 nm Isotype: IgG Uses: Fluorescence-activated cell sorting, flow cytometry, and protein microarraysEmission: 518 nm....
Application: IF
Host: Rabbit
488.00€ *
Review
DiPT
DiPT

Item number: Cay11550-25

5-Methoxy-N,N-diisopropyltryptamine (5-MeO DiPT) (Cay-11865) is a psychedelic hallucinogen which is abused worldwide. Known informally as 'foxy', this compound potently inhibits the re-uptake of dopamine, serotonin, and norepinephrine (IC50s = 65, 2.2, and 8.2 µM, respectively). DiPT is an uncommonly abused...
Keywords: N,N-Diisopropyltryptamine, N,N-bis(1-methylethyl)-1H-indole-3-ethanamine
Application: Analytical reference standard, Uncommonly abused psychedelic drug related to 5-MeO DiPT
CAS 14780-24-6
MW: 244.4 D
From 258.00€ *
Review
1-Palmitoyl-3-Lauroyl-rac-glycerol
1-Palmitoyl-3-Lauroyl-rac-glycerol

Item number: Cay28550-10

1-Palmitoyl-3-lauroyl-rac-glycerol is a diacylglycerol that contains palmitic acid (Cay-10006627) and lauric acid (Cay-10006626) at the sn-1 and sn-3 positions, respectively.Formal Name: hexadecanoic acid, 2-hydroxy-3-[(1-oxododecyl)oxy]propyl ester. CAS Number: 51604-53-6. Synonyms: 1-Palmitin-3-Laurin,...
Keywords: 1-Palmitin-3-Laurin, TG(16:0/0:0/12:0), hexadecanoic acid, 2-hydroxy-3-[(1-oxododecyl)oxy]propyl ester
Application: Diacylglycerol
CAS 51604-53-6
MW: 512.8 D
From 66.00€ *
Review
Kaempferol
Kaempferol

Item number: Cay11852-50

Kaempferol is a flavonoid which is abundant in a variety of plant leaves and fruits. It has diverse physiological activities through both direct and indirect effects. For example, kaempferol directly binds estrogen receptors alpha and beta, acting as an inverse agonist or agonist. It also acts as an antioxidant,...
Keywords: Nimbecetin, NSC 407289, NSC 656277, Pelargidenon, Rhamnolutein, Swartziol, Trifolitin,...
Application: Antioxidant, bioactive dietary flavonoid
MW: 286.2 D
From 60.00€ *
Review
TLR4-C34
TLR4-C34

Item number: Cay18512-50

Toll-like receptor 4 (TLR4) is activated by lipopolysaccharide (LPS), with LPS-binding protein, to initiate an innate immune response, which typically includes increased expression of TNFalpha. TLR4-C34 is a 2-acetamidopyranoside that inhibits TLR4 signaling in enterocytes and macrophages in vitro when used at 10...
Keywords: C34, TLR4-IN-C34, Toll-Like Receptor 4-C34, 1-methylethyl 2-(acetylamino)-2-deoxy-alpha-D-glucopyranoside, 3,4,6-triacetate
Application: TLR4 signaling inhibitor
CAS 40592-88-9
MW: 389.4 D
From 98.00€ *
Review
NVP-BEZ235 (hydrochloride)
NVP-BEZ235 (hydrochloride)

Item number: Cay21185-50

NVP-BEZ235 is a potent dual inhibitor of phosphatidylinositol 3-kinase (PI3K) and mTOR that is well tolerated, displays disease stasis when administered orally, and enhances the efficacy of other anticancer agents when used in in vivo combination studies. It inhibits PI3K isoforms and mutants with low nanomolar IC50...
Keywords: Dactolisib,...
Application: Antineoplastic, PI3K / mTOR inhibitor
CAS 2319647-83-9
MW: 506 D
From 43.00€ *
Review
SR 27897
SR 27897

Item number: Cay28511-50

SR 27897 is a nonpeptide cholecystokinin (CCK) receptor antagonist. It selectively binds to CCK1 receptors in rat pancreatic membranes (IC50 = 0.58 nM) over CCK2 receptors in guinea pig cortical membranes and gastrin receptors in guinea pig gastric gland suspensions (IC50s = 489 and 2,883 nM, respectively). SR 27897...
Keywords: Lintitript, 2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid
Application: Cholecystokinin-1 receptor antagonist
CAS 136381-85-6
MW: 411.9 D
From 158.00€ *
Review