13 products were found matching "Cay11285-100"!

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16-phenoxy tetranor Prostaglandin A2
16-phenoxy tetranor Prostaglandin A2

Item number: Cay10285-10

16-phenoxy tetranor PGA2 is a minor metabolite found in human plasma after intravenous administration of sulprostone. Its biological activity has not been studied or reported in the literature.Formal Name: 9-oxo-15R-hydroxy-16-phenoxy-17,18,19,20-tetranor-prosta-5Z,10,13E-trien-1-oic acid. CAS Number: 51639-10-2....
Keywords: 16-phenoxy tetranor PGA2, 9-oxo-15R-hydroxy-16-phenoxy-17,18,19,20-tetranor-prosta-5Z,10,13E-trien-1-oic acid
Application: Bioactive lipid assays
CAS 51639-10-2
MW: 370.4 D
From 82.00€ *
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Kaempferol
Kaempferol

Item number: Cay11852-100

Kaempferol is a flavonoid which is abundant in a variety of plant leaves and fruits. It has diverse physiological activities through both direct and indirect effects. For example, kaempferol directly binds estrogen receptors alpha and beta, acting as an inverse agonist or agonist. It also acts as an antioxidant,...
Keywords: Nimbecetin, NSC 407289, NSC 656277, Pelargidenon, Rhamnolutein, Swartziol, Trifolitin,...
Application: Antioxidant, bioactive dietary flavonoid
MW: 286.2 D
From 60.00€ *
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NVP-BEZ235 (hydrochloride)
NVP-BEZ235 (hydrochloride)

Item number: Cay21185-100

NVP-BEZ235 is a potent dual inhibitor of phosphatidylinositol 3-kinase (PI3K) and mTOR that is well tolerated, displays disease stasis when administered orally, and enhances the efficacy of other anticancer agents when used in in vivo combination studies. It inhibits PI3K isoforms and mutants with low nanomolar IC50...
Keywords: Dactolisib,...
Application: Antineoplastic, PI3K / mTOR inhibitor
CAS 2319647-83-9
MW: 506 D
From 43.00€ *
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MBD2 (human recombinant, methyl binding domain aa 150-220)
MBD2 (human recombinant, methyl binding domain aa 150-220)

Item number: Cay11286-100

DNA methylation occurs mainly at the 5'-position of cytosine rings (5-methylcytosine (5mC)). The 5mC bases are found largely in genomic regions with a high frequency of cytosines and guanines, called CpG islands. Methyl-CpG binding domain 2 (MBD2) protein specifically binds to methylated promoters on CpG islands....
Keywords: DMTase, DMTase, Demethylase, Demethylase, Methyl-CpG-binding protein MBD2, Methyl-CpG-binding protein MBD2,...
Application: Gene regulation studies
Expressed in: E.coli
MW: 34,8 kD
465.00€ *
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MeCP2 (human recombinant, methyl binding domain aa 77-166)
MeCP2 (human recombinant, methyl binding domain aa 77-166)

Item number: Cay11287-100

DNA methylation occurs mainly at the 5'-position of cytosine rings (5-methylcytosine (5mC)). The 5mC bases are found largely in genomic regions with a high frequency of cytosines and guanines, called CpG islands. Methyl-CpG binding protein 2 (MeCP2) specifically binds to methylated promoters on CpG islands and...
Keywords: MECP2, MeCp2, MeCp2, MeCp-2 protein, MeCp-2 protein, Methyl-CpG-binding protein 2, Methyl-CpG-binding protein 2
Application: Gene Regulation studies
Expressed in: E.coli
MW: 37,0 kD
465.00€ *
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CREB-binding protein bromodomain (human recombinant)
CREB-binding protein bromodomain (human recombinant)

Item number: Cay11288-100

Key Features Cayman's CBP bromodomain TR-FRET Assay Kit (Cay-600850) was developed using CREB-binding protein bromodomain (human recombinant) protein.Bulk sizes available upon request The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine...
Keywords: CBP, CREBBP, CREB-binding protein, CREB-binding protein, Histone lysine acetyltransferase CREBBP, Protein-lysine...
Application: Gene Regulation studies
Expressed in: E.coli
MW: 40,8 kD
481.00€ *
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Cladribine
Cladribine

Item number: Cay12085-10

Cladribine is a nucleoside analog of deoxyadenosine and prodrug form of 2-chlorodeoxyadenosine triphosphate (2-CdATP). It is triphosphorylated to Cd-ATP by the successive actions of deoxycytidine kinase, nucleoside monophosphate kinase, and nucleoside diphosphate kinase. Cladribine is cytotoxic to resting or...
Keywords: 2-Chlorodeoxyadenosine, Biodribin, Jk 6251, Leustatin, NSC 105014, RWJ 26251, 2-chloro-2'-deoxy-adenosine
Application: Nucleoside analog, Lymphocyte cytotoxic
CAS 4291-63-8
MW: 285.7 D
From 30.00€ *
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Iloprost
Iloprost

Item number: Cay18215-100

Iloprost is a second generation structural analog of prostacyclin (PGI) with about ten-fold greater potency than the first generation stable analogs, typified by carbaprostacyclin. Iloprost binds with equal affinity to the human recombinant IP and EP1 receptors with a Ki of 11 nM. Iloprost constricts the isolated...
Keywords: Ciloprost, 6,9alpha-methylene-11alpha,15S-dihydroxy-16-methyl-prosta-5E,13E-dien-18-yn-1-oic acid
Application: PGI analog
CAS 78919-13-8
MW: 360.5 D
From 92.00€ *
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UNC0646
UNC0646

Item number: Cay11085-10

G9a and G9a-like protein (GLP) are euchromatic histone-lysine methyltransferases (EHMT2 and EHMT1, respectively) that can heterodimerize with each other to methylate several proteins in addition to histone H3. UNC0646 is a potent and selective inhibitor of G9a and GLP activities in vitro (IC50s = 6 and 15 nM,...
Keywords: N-(1-cyclohexyl-4-piperidinyl)-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)propoxy]...
Application: Potent, selective EHMT1 / EHMT2 inhibitor
CAS 1320288-17-2
MW: 621.9 D
From 65.00€ *
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CBX5 (human recombinant)
CBX5 (human recombinant)

Item number: Cay11235-100

The heterochromatin protein 1 (HP1) family, which consists of three isoforms HP1alpha (CBX5), HP1beta (CBX1) and HP1gamma (CBX3) are chromatin-associated proteins involved in gene regulation and heterochromatin formation. CBX proteins have an N-terminal chromodomain, a C-terminal chromoshadow domain, and a hinge...
Keywords: CBX5, HP1A, HP1 alpha, HP1 alpha, Antigen p25, Antigen p25, Chromobox protein homolog 5, Chromobox protein homolog 5,...
Application: Gene Regulation studies
Expressed in: E.coli
MW: 24,1 kD
409.00€ *
Review
L-Homopropargyl Glycine (hydrochloride)
L-Homopropargyl Glycine (hydrochloride)

Item number: Cay11785-100

L-Homopropargyl glycine is a reactive methionine analog that contains an alkyne moiety. It is readily inserted into newly-synthesized proteins in place of methionine. L-Homopropargyl glycine can then be labeled or captured through click chemistry. This approach represents a fast, sensitive, and non-radioactive...
Keywords: Click Tag(TM) L-Homopropargyl Glycine, HPG, (2S)-2-amino-5-hexynoic acid
Application: Nascent protein synthesis detection
CAS 942518-19-6
MW: 163.6 D
From 43.00€ *
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Mouse Anti-DYKDDDDK IgG:DyLight(R) 650
Mouse Anti-DYKDDDDK IgG:DyLight(R) 650

Item number: Cay11265-100

Mouse anti-DYKDDDDK IgG (Clone M2) conjugated to DyLight(R) 650 Antibody: Mouse monoclonal anti-DYDDDDK IgG Isotype: IgG1 Clone: M2 Reactivity:  DYKDDDDK-tagged proteins Immunogen: DYKDDDDK IgG Dye: DyLight(R) 650 Excitation max. lambda: 652 nm Emission max. lambda: 672 nm Uses: Fluorescence-activated cell sorting,...
Application: IF
Host: Mouse
488.00€ *
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