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Item number: Cay17403-500

BQ-788 is a peptide endothelin type B (ETB) receptor antagonist (IC50 = 1.2 nM). It is selective for ETB over ETA receptors (IC50 = 280 nM), as well as angiotensin, calcitonin, or neuropeptide receptors at 10 µM. BQ-788 inhibits calcium mobilization induced by endothelin-1 (ET-1) in human Girrardi heart cells (IC50...

Keywords:	N-[[(2R,6S)-2,6-dimethyl-1-piperidinyl]carbonyl]-4-methyl-L-leucyl-1-(methoxycarbonyl)-D-tryptophyl-D-norleucine,...
Application:	Potent, selective endothelin receptor type B antagonist
CAS	156161-89-6
MW:	664.8 D

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