- Search results for AG-CP3-0001
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29 products were found matching "AG-CP3-0001"!
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Item number: AG-CP3-0001-M001
Potent and selective endothelin receptor A (ETA) antagonist, suppresses the ET-1-induced decrease of LPL activity, shows protective effects in ischemic acute renal failure, neuroprotective, anti-hypertensive, inhibits ET-1 receptor binding and blocks Ca2 mobilization, cellular contraction and MAP kinase activation,...
Keywords: | Endothelin Receptor A Antagonist BQ-123, cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu) Na |
Application: | Endothelin receptor A antagonist |
CAS | 136553-81-6 |
MW: | 609,7 D |
From 116.00€
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Item number: AG-CP3-0011-M005
Soluble in DMSO or ethanol. Potent, cell permeable and selective, reversible proteasome inhibitor. Blocks degradation of short-lived proteins and induces a heat shock response. NF-kappaB activation inhibitor through IkappaB degradation. Cell permeable, reversible peptide aldehyde inhibitor. Calpain and cathepsin...
Keywords: | Z-Leu-Leu-Leu-CHO, Z-LLL-CHO, Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal, MG132 |
Application: | Proteasome inhibitor |
CAS | 133407-82-6 |
MW: | 476 D |
From 22.00€
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Item number: AG-CP3-0044-M001
Retatrutide is a novel triple agonist peptide of the glucagon receptor (GCGR), glucose-dependent insulinotropic polypeptide receptor (GIPR) and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide inhibits human GCGR, GIPR and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively and mouse GCGR, GIPR,...
Keywords: | LY3437943, GGG Tri-agonist |
Application: | GCGR/GIPR/GLP-1R triple agonist peptide |
MW: | 4754.4 D |
From 132.00€
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Item number: AG-CP3-0002-M001
Cell permeable, non-selective broad-spectrum caspase inhibitor. Binds irreversibly to the catalytic site of caspase proteases - The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability - Inhibits ICE-family protease/caspase processing, leading to...
Keywords: | Z-VAD(OMe)-FMK, pan-Caspase Inhibitor, Z-Val-Ala-DL-Asp(OMe)-fluoromethylketone,... |
Application: | Caspase Inhibitor |
Expressed in: | Synthetic |
MW: | 467,5 D |
From 165.00€
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Item number: AG-CP3-0034-M001
Long-acting acylated glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic and antiobesity agent used clinically to treat type 2 diabetes mellitus. Binding to GLP-1R, activates AMP-activated protein kinase, consequently stimulates insulin secretion in pancreatic beta cells and suppresses glucagon secretion...
Keywords: | Arg34Lys26-(N-?-(?-Glu(N-?-hexadecanoyl)))-GLP-1(7-37), NN2211, NNC 90-1170, Victoza |
Application: | GLP-1 receptor agonist |
CAS | 204656-20-2 |
MW: | 3751.2 D |
From 88.00€
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Item number: AG-CP3-0007-M001
Synthetic. Soluble in DMSO. Cell permeable, non-toxic negative control for the caspase inhibitor Q-VD-OPh (Prod. No. AG-CP3-0006). Stable in aqueous environment. Several folds less inhibitory activity than Q-VD-OPh. Perfect for both in vitro and in vivo studies.
Keywords: | Q-Val-Glu-Oph, N-(2-Quinolyl)-L-valyl-L-glutamyl-(2,6-difluorophenoxy) methylketone |
Application: | pan-Caspase Inhibitor (Negative Control) |
MW: | 527,5 D |
176.00€
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Item number: AG-CP3-0012-M001
White to off-white solid. Soluble in DMSO, 0.1M sodium bicarbonate or 100% ethanol. Slightly soluble in methanol. Insoluble in water. Potent and selective endothelin B receptor (ETBR) antagonist.
Keywords: | ETB Receptor Antagonist,... |
Application: | Endothelin B receptor (EDNRB, ETBR) antagonist |
CAS | 156161-89-6 |
MW: | 663,8 D |
From 176.00€
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Item number: AG-CP3-0015-M001
Solid lyophilized powder. Soluble in DMSO. Potent, reversible and cell permeable proteasome inhibitor. Specifically inhibits the chymotrypsin-like activity of the proteasome, Calpain and cathepsin inhibitor, Apoptosis inducer in Rat-1 and PC12 cells via a p53-dependent pathway, Autophagy activator.
Keywords: | Z-LLNva-CHO, Proteasome Inhibitor |
Application: | Proteasome inhibitor |
CAS | 133407-86-0 |
MW: | 461,6 D |
From 22.00€
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Item number: AG-CP3-0006-M001
The IC50 range for caspases -1, -3, -8, -9, -10, and -12 is 25-400 nM. Synthetic. Soluble in DMSO. Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the...
Keywords: | Q-Val-Asp-Oph, N-(2-Quinolyl)-L-valyl-L-aspartyl-(2,6-difluorophenoxy) methylketone |
Application: | pan-Caspase Inhibitor |
MW: | 513,5 D |
From 187.00€
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Item number: AG-CP3-0008-M001
Synthetic. Soluble in water. Selective cell permeable and irreversible MALT1 inhibitor. Inhibits NF-?B-dependent gene expression and affects the growth, proliferation and survival of activated B cell-like diffuse large B cell lymphomas (ABC-DLBCL) and germinal center B cell like diffuse large B cell lymphoma...
Keywords: | Z-Val-Arg-Pro-DL-Arg-FMK . TFA |
Application: | MALT1 inhibitor |
MW: | 790,8 D |
From 297.00€
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Item number: AG-CP3-0024-M001
Solid lyophilized powder. Soluble in DMSO. Highly potent and selective cell permeable inhibitor of the proteasome. Inhibits the chymotrypsin-like and caspase-like peptidase activity of the proteasome, Calpain and cathepsin inhibitor, Autophagy activator, Similar structure as MG-132 (AG-CP3-0011) but much higher...
Keywords: | Z-LLL-B(OH)2, Proteasome Inhibitor III |
Application: | Proteasome inhibitor |
CAS | 179324-22-2 |
MW: | 491,4 D |
From 77.00€
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Item number: AG-CP3-0021-M001
Solid lyophilized powder. Soluble in DMSO. Reversible and cell permeable proteasome inhibitor. Specifically inhibits the chymotrypsin-like activity of the proteasome, Calpain and cathepsin inhibitor, Does not inhibit the peptidyl-glutamyl peptide hydrolyzing activity of MPC.
Keywords: | Z-LLF-CHO, Proteasome Inhibitor II |
Application: | Proteasome inhibitor |
CAS | 133429-58-0 |
MW: | 509,7 D |
From 66.00€
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