Off-white powder. Soluble in water, DMSO or methanol. Modified base of mammalian DNA, involved in regulation of stem cell processes, cellular development, neurodegeneration and carcinogenesis, important epigenetic marker, related to bacimethrin (BVT-0226).

Tide Fluor(TM)6 (TF6) family has the spectral properties similar to those of Cy5.5, IRDye 700 and Alexa Fluor 680. Their fluorescence is pH-independent from pH 3 to 11. These characteristics make this new dye family more robust to pH-sensitive assays. In some cases TF6-labeled peptides and nucleotides exhibit...

YYA-021 is a small molecule CD4 mimetic that competitively inhibits gp120 from interacting with CD4, preventing HIV entry into cells. It inhibits infection of PM1/CCR5 cells from lab isolates of the HIV-1 strains IIIB (X4, Sub B) and 89.6 (dual, Sub B) (IC50s = 23 and 41 µM, respectively) as well as clinical...

Atreleuton is an inhibitor of 5-lipoxygenase (5-LO, IC50 = 23 nM in rat basophil leukemia cell lysates). It inhibits leukotriene B4 (LTB4, Cay-20110) formation induced by A23187 (Cay-11016, Cay-22030) in isolated human whole blood (IC50 = 160 nM). Atreleuton inhibits LTE4 and LTB4 biosynthesis in the peritoneal...

Protein function: Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:2803308, PubMed:10910050, PubMed:10864933). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6...