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PE 22-28 (acetate)
PE 22-28 (acetate)

Item number: Cay39986-5

PE 22-28 is a peptide inhibitor of the two-pore domain potassium channel K2P2.1/TREK1 (IC50 = 0.1 nM in HEK293 cells expressing the human channel) and a fragment of spadin (Cay-36762). It is selective for K2P2.1/TREK1 over K2P10.1 /TREK2, K2P13.1/TRAAK, K2P18.1/TRESK, and K2P3.1/TASK1 in HEK293 cells expressing the...
Keywords: Gly-Val-Ser-Trp-Gly-Leu-Arg-OH, glycyl-L-valyl-L-seryl-L-tryptophylglycyl-L-leucyl-L-arginine, acetate
Application: K2P2.1/TREK1 peptide inhibitor
MW: 773.9 D
From 119.00€ *
Review
D-threo-Biopterin
D-threo-Biopterin

Item number: Cay29986-5

D-threo-Biopterin is a pterin originally isolated from D. discoideum. It enhances luminol (Cay-16803) chemiluminescence induced by the oxidant chloramine-T in a cell-free assay when used at a concentration of 100 µM.Formal Name: 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-4(3H)-pteridinone. CAS Number: 13019-52-8....
Keywords: 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-4(3H)-pteridinone
Application: Luminol chemiluminescence enhancer
CAS 13019-52-8
MW: 237.2 D
From 77.00€ *
Review
Dimethoxycurcumin
Dimethoxycurcumin

Item number: Cay10009986-5

Dimethoxycurcumin is a derivative of curcumin (Cay-81025) that has anti-inflammatory and antioxidant activities. It inhibits mitogen-induced proliferation of CD4+ T cells, CD8+ T cells, and B cells, as well as secretion of IL-2, IL-4, IL-6, and IFN-gamma induced by concanavalin A (Cay-14951) in isolated human...
Keywords: Di-O-methylcurcumin, 1,7-bis(3,4-dimethoxyphenyl)-1,6-heptadiene-3,5-dione
Application: Curcumin analog
CAS 160096-59-3
MW: 396.4 D
From 39.00€ *
Review
Diquafosol (sodium salt)
Diquafosol (sodium salt)

Item number: Cay33971-25

Diquafosol is an agonist of purinergic P2Y2 and P2Y4 receptors (EC50s = 0.1 and 0.4 µM, respectively, in calcium mobilization assays). It is selective for P2Y2 and P2Y4 receptors over P2Y6 receptors (EC50 = 20 µM). Ocular application of diquafosol (0.1 and 1% w/v) induces the release of mucin-like glycoproteins from...
Keywords: INS365, KPY 998, uridine 5'-(pentahydrogen tetraphosphate), P'''->5'-ester with uridine, tetrasodium salt
Application: P2Y2 / P2Y4 receptor agonist
CAS 211427-08-6
MW: 878.2 D
From 142.00€ *
Review