BAFF (aa134-285, Soluble (human, rec.)

BAFF (aa134-285, Soluble (human, rec.)
%
Item number Size Datasheet Manual SDS Delivery time Quantity Discount Price
AG-40B-0016-C010 10 µg -

3 - 9 business days*

10 %
231.00€
207.90€
AG-40B-0016-3010 30 µg (3 x 10 µg) -

3 - 9 business days*

10 %
462.00€
415.80€
 
(3 x 10µg). Human BAFF (amino acids 134-285) is fused at the N-terminus to a FLAG(R)-tag.... more
Product information "BAFF (aa134-285, Soluble (human, rec.)"
(3 x 10µg). Human BAFF (amino acids 134-285) is fused at the N-terminus to a FLAG(R)-tag. Lyophilized. Contains PBS. BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, Rheumatoid Arthritis (RA), Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE). BAFF is also increased levels in some lymphoid cancers.
Keywords: BLyS, TALL-1, CD257, B-cell activating factor, TNFSF 13B, Tumor necrosis factor ligand superfamily member 13B
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-40B-0016

Properties

Application: Bioassays
Conjugate: No
Host: E.coli
Species reactivity: human
MW: 23 kD
Format: Lyophilized

Database Information

KEGG ID : K05476 | Matching products
UniProt ID : Q9Y275 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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