- Search results for Cay600073
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14 products were found matching "Cay600073"!
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Item number: Cay600037-1
Synonyms: sEH (human recombinant). Formulation: 12 µl of human recombinant Soluble Epoxide Hydrolase (sEH).
Keywords: | sEH (human recombinant) |
Application: | Kit component |
114.00€
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Item number: Cay600007-384
Prostaglandin D2 (PGD2) is synthesized by hematopoietic-type PGD-synthase (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. H-PGDS is therefore a key target for development of selective, potent inhibitors for therapeutic use against these diseases. Cayman's H-PGDS...
Keywords: | H-PGDS FP-Based Inhibitor Screening Assay Kit - Green, Prostaglandin D Synthase (hematopoietic-type) Fluorescence... |
Application: | PGDS inhibitor screening |
Species reactivity: | human |
From 554.00€
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Item number: Cay600173-10
Formulation: 10 ml of BSA blocking solution. Origin: Animal/Bovine.
Application: | Kit component |
36.00€
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Item number: Cay10006973-10
Pravadoline is a nonacidic, aminoalkylindole analgesic agent that inhibits cyclooxygenase. Like NSAIDs, pravadoline inhibits prostaglandin synthesis (IC50 = 5 µM in mouse brain microsomes) and displays antinociceptive activity (ED50 = 26 mg/kg in an acetylcholine-induced writhing assay in mice). In contrast to...
Keywords: | WIN 48,098, (4-methoxyphenyl)[2-methyl]-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]-methanone |
Application: | Analytical reference standard, COX inhibitor, NSAID |
CAS | 92623-83-1 |
MW: | 378.5 D |
From 274.00€
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Item number: Cay10007663-1
SREBPs, including SREBP-1a, SREBP-1c, and SREBP-2, constitute a family of basic helix-loop-helix (bHLH) transcription factors that play a critical role in lipid homeostasis by regulating genes involved in cholesterol and fatty acid metabolism. SREBP-2 regulates cholesterol synthesis by activating the transcription...
Keywords: | Anti-BHLHD2, Anti-bHLHd2, Anti-SREBP-2 {ECO:0000303|PubMed:15461802}, Anti-Class D basic helix-loop-helix protein 2,... |
Application: | ICC, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
456.00€
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Item number: Cay10007763-100
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,5)-P2 (1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C8:0 fatty...
Keywords: | DOPI-3,5-P2, Phosphatidylinositol-3,5-bisphosphate C-8, 1-(1,2-dioctanoylphosphatidyl)inositol-3,5-bisphosphate, trisodium... |
Application: | Bioactive lipid assays |
MW: | 812.5 D |
From 68.00€
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Item number: Cay10007653-1
Rho-associated kinase (ROCK), activated by GTP-linked Rho, phosphorylates targets that are involved in cytoskeletal remodeling, smooth muscle contraction, and neuronal development. H-1152 is a potent, specific, ATP-competitive, and cell permeable inhibitor of ROCK (Ki = 1.6 nM). It is a more potent inhibitor of ROCK...
Keywords: | 5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-4-methyl-isoquinoline, dihydrochloride |
Application: | ROCK inhibition |
CAS | 451462-58-1 |
MW: | 392.3 D |
From 48.00€
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Item number: Cay10007263-100
(±)14(15)-EET is a metabolite of arachidonic acid (Cay-90010, Cay-90010.1, 10006607) that is formed via epoxidation of arachidonic acid by cytochrome P450. It prevents increases in leukotriene B4 (LTB4, Cay-20110), ICAM-1, and chemokine (C-C motif) ligand 1 (CCL2) induced by oxidized LDL in primary rat pulmonary...
Keywords: | (±)14,15-EET, (±)14,15-EpETrE, (±)14,15-epoxy-5Z,8Z,11Z-eicosatrienoic acid |
Application: | Standard |
CAS | 197508-62-6 |
MW: | 320.5 D |
287.00€
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COVID-19 Research
Item number: Cay10007963-5
E-64 is a fungal metabolite originally isolated from Aspergillus japonicus that has diverse biological activities. It inhibits a variety of cysteine proteases, including cathepsins B, H, and L, as well as papain, ficin, and bromelain, but not the serine proteases plasmin, trypsin, and tissue kallikrein or the...
Keywords: | (2S,3S)-3-[[[(1S)-1-[[[4-[(aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]-2-oxiranecarboxylic... |
Application: | Cysteine protease inhibitor |
CAS | 66701-25-5 |
MW: | 357.4 D |
From 73.00€
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Item number: Cay10005673-5
HU-331 (Cay-10005673) is an analytical reference standard categorized as an oxidative degradation product of the phytocannabinoid cannabidiol (CBD, Cay-ISO60156, Cay-90080). This product is intended for research and forensic applications.Formal Name:...
Keywords: | Cannabidiol Hydroxy Quinone, Cannabidiolquinone, CBDHQ, CBDQ,... |
Application: | Analytical reference standard, oxidative degradation cannabidiol (CBD) product |
CAS | 137252-25-6 |
MW: | 328.5 D |
From 82.00€
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Item number: Cay10006373-1
Sphingosine-1-phosphate (S1P) exerts its activity by binding to five distinct G-protein-coupled receptors, S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P3 couples to Gi/o-ERK, Gq-PLC, and G12/13-Rho axes to mediate S1P-induced cell proliferation, survival, migration, and related signaling...
Keywords: | Anti-EDG3, Anti-S1P3, Anti-S1P3, Anti-S1PR3, Anti-S1P receptor 3, Anti-S1P receptor 3, Anti-S1P receptor Edg-3, Anti-S1P... |
Application: | ICC, WB |
Host: | Rabbit |
422.00€
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Item number: Cay10007863-10
1,2-Dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at the sn-1 and sn-2 positions. It effectively binds the C1 domain to activate conventional protein kinase C forms and serves as a substrate for DAG kinases and multisubstrate lipid kinase.Formal Name: 9Z-octadecenoic acid,...
Keywords: | (±)-1,2-Diolein, rac-Glycerol 1,2-dioleate, 9Z-octadecenoic acid, 1,1'-[1-(hydroxymethyl)-1,2-ethanediyl] ester |
Application: | PKC activator, kinase substrate |
CAS | 2442-61-7 |
MW: | 621 D |
From 60.00€
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