45 products were found matching "B0003-66B"!

Human BAFF is a newly discovered novel ligand of the TNF family. BAFF plays an important role as costimulator of B cell proliferation and function. Source: Recombinant protein corresponding to human soluble BAFF, aa134-285, expressed in E. coli. Molecular Weight: ~17kD, Biological Activity: Measured by its...

The Anthrax toxin receptor (ATR) was initially discovered as the tumor endothelial marker 8 (TEM8) (1). This protein, which exists in three isoforms (36, 40, and 60 kD), is highly expressed in tumor vessels as well as in the vasculature of developing embryos, suggesting that it may normally play a role in...

B lymphocyte stimulator (BLyS), a member of the tumor necrosis factor (TNF) superfamily of cytokines, induces B-cell proliferation and immunoglobulin secretion and is a key regulator of peripheral B-cell populations in vivo.. BLyS is made by immune-cells called monocytes and macrophages. When monocytes and...

Bcl-w is a pro-survival (apoptotic) member of the Bcl-2 family, a family involved in the regulation of cellular apoptosis at the mitochondrion. Relative to its Bcl-2 counterparts there is considerably less data on this prticular protein. Studies of the related gene in mice indicated a role in the survival of NGF-...

Bad is a 22kD protein that activates apoptosis. It exhibits sequence homology to Bcl-2, a protein that prevents apoptosis, within its BH1 and BH2 domains (1). Bad heterodimerizes with Bcl-Xl and Bcl-2 and reverses the apoptosis suppression effect by Bcl-Xl but not Bcl-2. Bad is phosphorylated by Raf-1, a...

Tumor Endothelial Marker 8 (TEM8), also called ATR1, is a glycoprotein of the anthrax toxin receptor family that is expressed by endothelial cells. Type I transmembrane isoforms of 564 aa (80-85 kD) and 368 aa (60 kD) and potentially secreted isoforms of 330 aa and 297 aa (45 kD) are differentially expressed. All...

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin...

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL-1 (for TNF-and ApoL-related...

CD268 is a member of the tumor necrosis factor receptor family, which is expressed by B cells. CD268 plays a role in BAFF induced B cell development and survival, and is thought to be involved in B cell autoimmune diseases, Applications: Suitable for use in Immunohistochemistry and Western Blot. Other applications...

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin...

Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin...

Applications: , Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-2ug/ml detected Blys/TALL-1/BAFF/THANK in RIPA lysates from Jurkat cells. A previous lot detected Blys/TALL1/BAFF/THANK, in HeLa nuclear extract., Optimal dilutions to be determined by the...