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Atropine
Atropine

Item number: Cay12008-500

Atropine is a naturally occurring tropane alkaloid extracted from plants of the family Solanaceae including deadly nightshade (A. belladonna). It is a non-selective, competitive antagonist of the muscarinic acetylcholine receptor types M1, M2, M3, M4, and M5 (pKBs range from 8.9-9.8). Atropine increases firing of...
Keywords: DL-Hyoscyamine, Tropine tropate, alpha-(hydroxymethyl)-(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester-benzeneacetic acid
Application: Muscarinic acetylcholine receptor antagonist
CAS 51-55-8
MW: 289.4 D
From 34.00€ *
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Cyclosporin A
Cyclosporin A

Item number: Cay12088-25

Cyclosporin A is an immunosuppressant drug that binds cyclophilin D, inhibiting the phosphatase activity of calcineurin in T cells (IC50 = 5 nM). It blocks the transcription of genes involved in T cell activation by interfering with the calcineurin-driven nuclear import of the transcription factor NFAT. Because of...
Keywords: NSC 290193
Application: Immunosuppressant, Calcineurin inhibitor
CAS 59865-13-3
MW: 1202.6 D
From 43.00€ *
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KRN 7000
KRN 7000

Item number: Cay11208-1

KRN 7000 is a potent synthetic alpha-galactosylceramide, which, in association with the antigen-presenting CD1d protein, activates NKT immune cells. As these cells have important roles in the rejection of malignant tumors and in the regulation of several autoimmune diseases, KRN 7000 has activity in many diseases,...
Keywords: N-[(1S,2S,3R)-1-[(alpha-D-galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl]-hexacosanamide
Application: Synthetic alpha-galactosylceramide, Bioassays
CAS 158021-47-7
MW: 858.3 D
From 265.00€ *
Review