Apolipoprotein H (beta 2 Glycoprotein 1, ApoHb2gp1) BioAssay ELISA Kit

Apolipoprotein H (beta 2 Glycoprotein 1, ApoHb2gp1) BioAssay ELISA Kit
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A2299-81.1 1 kit - -

3 - 19 business days*

1,057.00€
 
Apolipoprotein-H, also known as beta 2-Glycoprotein I (beta 2GPI), is a plasma glycoprotein that... more
Product information "Apolipoprotein H (beta 2 Glycoprotein 1, ApoHb2gp1) BioAssay ELISA Kit"
Apolipoprotein-H, also known as beta 2-Glycoprotein I (beta 2GPI), is a plasma glycoprotein that circulates at a concentration of 200ug/ml (4uM). Synthesized in the liver, beta 2GPI is a single chain molecule of 48kD, consisting of five repeating internally , disulfide-bonded structures referred to as sushi domains. Relative to other glycoproteins, beta 2GPI has an unusually high content of cysteine (6.2%), proline (8.3%) and carbohydrate (19%). Almost half the circulating beta 2GPI in plasma is associated with lipoproteins of all major fractions. beta 2GPI has been demonstrated to bind negatively charged phospholipids, heparin and platelets. Although the precise function(s) are as yet unknown, beta 2GPI has been demonstrated to interfere with blood coagulation by competitively binding to negatively charged phospholipid surfaces exposed during cell activation or damage. Recent evidence also implicates beta 2GPI as a cofactor recognized by , anti-phospholipid antibodies present in some autoimmune disorders such as systemic lupus erythematosus (SLE). Materials Supplied: Antibodies for 5x96 well plates, Kit Components: A2299-81A: Capture Antibody, 1x500ul, Supplied as a liquid in 50% glycerol. Purified by immunoaffinity chromatography. Pab goat x human for coating ELISA plates. A2299-81B: Detecting Antibody (HRP), 1x500ul, Supplied as a liquid in 50% glycerol. Purified by immunoaffinity chromatography. Pab goat x human for detection. Storage and Stability: For long-term storage, aliquot and store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: APOH, B2G1, B2GPI, Apo-H, Beta(2)GPI, APC inhibitor, Apolipoprotein H, Beta-2-glycoprotein I, Beta-2-glycoprotein 1, Anticardiolipin cofactor, Activated protein C-binding protein
Supplier: United States Biological
Supplier-Nr: A2299-81

Properties

Application: ELISA
Species reactivity: human
Format: Solid Phase

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Apolipoprotein H (beta 2 Glycoprotein 1, ApoHb2gp1) BioAssay ELISA Kit"
Write a review
or to review a product.
Viewed