- Search results for Cay10004872-1
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16 products were found matching "Cay10004872-1"!
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Item number: Cay10010487-25
Lubiprostone is an activator of chloride channel protein 2 (ClC-2) and a bicyclic derivative of prostaglandin E1 (PGE1, Cay-13010). It induces chloride currents in HEK293 cells expressing recombinant human ClC-2 (EC50 = ~17 nM), but not CFTR, chloride channels. Lubiprostone (1 µM) induces short-circuit currents, a...
Keywords: | RU-0211, SPI-0211, 16,16-difluoro-11alpha-hydroxy-9,15-dioxo-prostan-1-oic acid |
Application: | ClC-2 activator |
CAS | 136790-76-6 |
MW: | 390.5 D |
From 84.00€
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Item number: Cay10004372-1
(±)-Nutlin-3 is a racemic mixture of the p53-Mdm2 protein-protein interaction inhibitor (-)-nutlin-3 (Cay-18585) and its less active enantiomer (+)-nutlin-3 (Cay-10009816). In vivo, (±)-nutlin-3 (200 mg/kg twice daily) reduces tumor volume in an SJSA-1 osteosarcoma mouse xenograft model.Formal Name:...
Keywords: | rel-4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-pi... |
Application: | Cell cycle arrest promotor |
CAS | 548472-68-0 |
MW: | 581.5 D |
From 50.00€
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Item number: Cay10004272-1
Peroxisome proliferator-activated receptor delta (PPARdelta) stimulation or over-expression in adipocytes leads to increased fatty acid oxidation, improved exercise tolerance, and resistance to obesity. GW 501516 is the first highly selective synthetic PPARdelta agonist available. GW 501516 binds to human PPARdelta...
Keywords: | GW 1516, 2-[2-methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]-acetic acid |
Application: | PPAR delta agonist |
CAS | 317318-70-0 |
MW: | 453.5 D |
From 60.00€
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Item number: Cay10004873-1
Formulation: A lyophilized powder.
Application: | Kit component |
50.00€
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Item number: Cay10004802-1
Synonyms: 2-thio PAF (substrate), 2-Thio PAF PAF-AH Inhibitor Screening (substrate), 2-Thio PAF PAF-AH (substrate).
Keywords: | 2-thio PAF (substrate), 2-Thio PAF PAF-AH (substrate), 2-Thio PAF PAF-AH Inhibitor Screening (substrate) |
Application: | Kit component |
76.00€
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Item number: Cay10009872-500
1-Stearoyl-2-arachidonoyl-d8-sn-glycerol (SAG-d8) is intended for use as an internal standard for the quantification of SAG (Cay-10008650) by GC- or LC-MS. Many protein kinase C (PKC) isoforms require activation via second messengers including Ca2+, diacylglycerol (DAG), and/or a phospholipid in order to...
Keywords: | SAG-d8, 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-5,6,8,9,11,12,14,15-d8-sn-glycerol |
Application: | Standard |
MW: | 653.1 D |
From 77.00€
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Item number: Cay10008872-1
CAY10503 is a proapoptotic, antiproliferative compound that is able to arrest cell cycle progression in the G0-G1 phase. CAY10503 inhibits the growth of HL60, multidrug resistant HL60R, and K562 cells with IC50 values of 7.0, 23, and 20 µM, respectively. Accumulation of HL60 cells in G0-G1 occurred within eight...
Keywords: | 4-(4-hydroxyphenyl)phenyl-3,5-benzenediol |
Application: | Proapoptotic reagent |
CAS | 890854-82-7 |
MW: | 278.3 D |
From 38.00€
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Item number: Cay10004387-1
Sulindac sulfide is an active metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor sulindac (Item No, 10004386). It inhibits both COX-1 and COX-2 (IC50s = 1.9 and 1.21 µM, respectively), whereas the parent compound, sulindac, is much less effective (IC50 = 58 µM for COX-2 and > 100 µM for...
Keywords: | 5-fluoro-2-methyl-1Z-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid |
Application: | Aldose reductase inhibitor, COX1/COX2 inhibitor |
CAS | 49627-27-2 |
MW: | 340.4 D |
From 43.00€
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Item number: Cay10006872-1
Formulation: A solution of 95 uM Arg-Glu(EDANS)-Ile_his-Pro-Phe-His-Leu-Val-Ile-His-Lys(Dabvyl)-Arg in dimethyl sulfoxide.
Application: | Kit component |
228.00€
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Item number: Cay14872-1
Lucigenin is a chemiluminescent probe used to detect superoxide production and the presence of chloride. It can be used to detect superoxide production by enzymatic and cellular sources. It is a sensitive method that has been applied to the monitoring of superoxide production from xanthine oxidase, microsomal NADPH...
Keywords: | L-6,868, NSC 151912, 10,10'-dimethyl-9,9'-biacridinium, dinitrate |
Application: | Superoxide indicator, Chloride indicator |
CAS | 2315-97-1 |
MW: | 510.5 D |
From 43.00€
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Item number: Cay100028-1
Sterol O-acyltransferase 1 (SOAT-1), also known as acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1), is an enzyme encoded by ACAT1 in humans that catalyzes the intracellular formation of cholesterol esters from cholesterol and long-chain fatty acyl-coenzyme A. It is ubiquitously expressed and localized to the...
Keywords: | Anti-ACAT-1, Anti-ACAT-1, Anti-Sterol O-acyltransferase 1, Anti-Sterol O-acyltransferase 1, Anti-Cholesterol... |
Application: | IF, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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