Anti-phospho-TSC2 (Ser1420) (Tuberin, Tuberous Sclerosis 2 Protein, TSC4) (Azide free) (APC)

Anti-phospho-TSC2 (Ser1420) (Tuberin, Tuberous Sclerosis 2 Protein, TSC4) (Azide free) (APC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
T9100-25G7-APC.200 200 µl - -

3 - 19 business days*

993.00€
 
Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor... more
Product information "Anti-phospho-TSC2 (Ser1420) (Tuberin, Tuberous Sclerosis 2 Protein, TSC4) (Azide free) (APC)"
Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Applications: Suitable for use in FLISA and Dot Blot. Other applications not tested. Recommended Dilution: FLISA: 1:1,000 , Dot Blot: 1:500, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-phospho-TSC2, Anti-phospho-TSC4, Anti-phospho-Tuberin, Anti-phospho-Tuberous sclerosis 2 protein
Supplier: United States Biological
Supplier-Nr: T9100-25G7-APC

Properties

Application: FLISA, Dot Blot
Antibody Type: Polyclonal
Conjugate: APC
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Ser1420 of human TSC2 (KLH).
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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