19 products were found matching "P9198-08C"!

PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta, both bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution:...

Applications: , Suitable for use in ELISA, Western Blotting. Other applications not tested. Recommended Dilution: Western Blot: 1:1000-1:5000 for antiserum and 1-10ug/ml for affinity pure antibody using ECL., ELISA: 1:10,000-50,000 for neat serum and 0.5-1ug/ml for affinity pure. Control peptide can be used to coat...

A novel gene PUMA (p53 upregulated modulator of apoptosis) is a target for activation by the p53 tumor-suppressor gene. p53 functions as a transcriptional activator, and influences p53-inducible genes that play a role in the induction of apoptosis in response to p53. Antisense inhibition of PUMA expression reduced...

Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 up-regulated , modulator of apoptosis) and bbc3 (for Bcl-2...

Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) and bbc3 (for Bcl-2 binding...

A novel p53 inducible pro-apoptotic gene was identified recently and designated PUMA (for p53 upregulated modulator of apoptosis) in human and mouse. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome...

PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in...

PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in...

A novel gene PUMA (p53 upregulated modulator of apoptosis) is a target for activation by the p53 tumor-suppressor gene. p53 functions as a transcriptional activator, and influences p53-inducible genes that play a role in the induction of apoptosis in response to p53. Antisense inhibition of PUMA expression reduced...

PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta, both bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution:...

PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta, both bind Bcl-2, localize to the mitochondria, and induce Cytochrome c release and apoptosis in response to p53. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution:...

p53 tumor antigen is found in increased amounts in a wide variety of transformed cells. The protein is also detectable in many actively proliferating, nontransformed cells, but it is undetectable or present at low levels in resting cells. P53 tumor-suppressor protein functions to inhibit the growth of tumor cells....