Epidermal growth factor (EGF) receptor is a 170kD single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation (1,2). Tyrosine 845 resides in the activation...

Applications: , Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5ug/ml for HRPO/ECL detection, Use 0.5% caseine,1% PEG 4000, 1% Polyvinylpyrrolidone (PVP) 0.1% Tween 20, 2xPBS for blocking., ELISA: 0.05ug/ml, Optimal dilution determined by the...