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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-J95 | 50 µg | - | - |
6 - 10 business days* |
684.00€
|
Anti-Androgen Receptor pY267 was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-phospho-Androgen Receptor (Tyr267)"
Anti-Androgen Receptor pY267 was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with human and chimpanzee based on 100% sequence homology. Cross-reactivity with Androgen Receptor pY267 from other sources has not been determined. Androgen Receptor detects human Androgen receptor. The androgen receptor (AR) is an ~110 kDa androgen-dependent transcription factor that is a member of the steroid/nuclear receptor gene superfamily. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and brain. Abnormalities in the AR signaling pathway have been linked to a number of diseases, including prostate cancer, Kennedy's disease and male infertility. The PI3K/Akt signaling pathway plays an important role in regulating AR activity through phosphorylation of AR at Ser213/210 and Ser791/790. Growth factors or cytokines may induce phosphorylation of AR through the PI3K/Akt pathway. Activation of the PI3K/AKt pathway is thought to have a survival role in prostate cancer by protecting cells from apoptosis. Anti-Androgen Receptor Antibody is ideal for investigators involved in neuroscience, cytokines and growth factors, and transcription factors.
Keywords: | Anti-phospho-AR, Anti-phospho-DHTR, Anti-phospho-Androgen receptor, Anti-phospho-Dihydrotestosterone receptor, Anti-phospho-Nuclear receptor subfamily 3 group C member 4 |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-J95 |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | synthetic peptide corresponding to the internal region of human ANDR protein. |
Format: | Purified |
Database Information
KEGG ID : | K08557 | Matching products |
UniProt ID : | P10275 | Matching products |
Gene ID | GeneID 367 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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