Anti-phospho-Androgen Receptor (Tyr267)

Anti-phospho-Androgen Receptor (Tyr267)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-J95 50 µg - -

6 - 10 business days*

684.00€
 
Anti-Androgen Receptor pY267 was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-phospho-Androgen Receptor (Tyr267)"
Anti-Androgen Receptor pY267 was affinity purified from monospecific antiserum by immunoaffinity chromatography. A BLAST analysis was used to suggest cross-reactivity with human and chimpanzee based on 100% sequence homology. Cross-reactivity with Androgen Receptor pY267 from other sources has not been determined. Androgen Receptor detects human Androgen receptor. The androgen receptor (AR) is an ~110 kDa androgen-dependent transcription factor that is a member of the steroid/nuclear receptor gene superfamily. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and brain. Abnormalities in the AR signaling pathway have been linked to a number of diseases, including prostate cancer, Kennedy's disease and male infertility. The PI3K/Akt signaling pathway plays an important role in regulating AR activity through phosphorylation of AR at Ser213/210 and Ser791/790. Growth factors or cytokines may induce phosphorylation of AR through the PI3K/Akt pathway. Activation of the PI3K/AKt pathway is thought to have a survival role in prostate cancer by protecting cells from apoptosis. Anti-Androgen Receptor Antibody is ideal for investigators involved in neuroscience, cytokines and growth factors, and transcription factors.
Keywords: Anti-phospho-AR, Anti-phospho-DHTR, Anti-phospho-Androgen receptor, Anti-phospho-Dihydrotestosterone receptor, Anti-phospho-Nuclear receptor subfamily 3 group C member 4
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-J95

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: synthetic peptide corresponding to the internal region of human ANDR protein.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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