Anti-p53, aa20-25 (Oncogene Protein, TP53, Cellular Tumor Antigen p53, Antigen NY-CO-13, Phosphoprot

Anti-p53, aa20-25 (Oncogene Protein, TP53, Cellular Tumor Antigen p53, Antigen NY-CO-13, Phosphoprot
Item number Size Datasheet Manual SDS Delivery time Quantity Price
P1001-26T1.25 25 µg - -

3 - 19 business days*

416.00€
P1001-26T1.100 100 µg - -

3 - 19 business days*

682.00€
 
p53 is a 53kD protein that forms tetramers and functions as a tumor suppressor and... more
Product information "Anti-p53, aa20-25 (Oncogene Protein, TP53, Cellular Tumor Antigen p53, Antigen NY-CO-13, Phosphoprot"
p53 is a 53kD protein that forms tetramers and functions as a tumor suppressor and transcriptional activator of genes that inhibit growth and/or invasion, cell cycle checkpoint after irradiation, DNA repair, apoptotic induction, signal transduction, and cell adhesion. This protein is localized to the nucleus when activated and can be upregulated by genotoxic or other cellular stresses. p53 is modified by phosphorylation, acetylation, ribosylation, ubiquitination, and sumoylation, ubiquination targets p53 for degradation via mdm2. This protein interacts with a variety of proteins including mdm2, mdmx, topoisomerase I, PML3, Bcl-XL, Bcl-2, Chk1, JNK, p38, HIPK2, CK2, DNA-PK, p300/CBP, PCAF, PARP1, and HDAC1-3. Mutant p53 associates with p63 and p73. Applications: Suitable for use in Immunoprecipitation and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 0.5-1ug/ml for each mini-gel, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: P1001-26T1

Properties

Application: IP, WB
Antibody Type: Monoclonal
Clone: DO-1
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: P53 N-terminal linear epitope aa20-25.
Purity: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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