Anti-p53 (Tumor Suppressor Protein, Oncogene Protein)

Anti-p53 (Tumor Suppressor Protein, Oncogene Protein)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
P1001-32D.150 150 µg - -

3 - 19 business days*

848.00€
 
The C terminus of p53 is rich in lysines, which are subjected to different modifications to... more
Product information "Anti-p53 (Tumor Suppressor Protein, Oncogene Protein)"
The C terminus of p53 is rich in lysines, which are subjected to different modifications to regulate p53 activity. p53 tumor suppressor gene mutations are one of the most common genetic alterations in human tumors, including lymphomas. Altering or inactivating p53 by mutation or reaction with oncogenes or viruses may cause depletion of p53, or conversion of p53 from a tumor suppressor gene to a transforming oncogene. The nuclear protein p53 is associated with cell transformation and proliferation, with definitive possibilities as a marker in malignant lymphoma progression. p53's role in the multistep process leading to cancer is still being investigated, with an emphasis on its relation and control over additional tumor suppressors. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: P1001-32D

Properties

Application: ELISA
Antibody Type: Monoclonal
Clone: 9F633
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: KLH-conjugated synthetic peptide SHLKSKKGQST corresponding to aa367-377 of human tumor suppressor p53
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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