Anti-XPC

Anti-XPC
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-122A-T 10 µl (2 µg) -

2 - 8 business days*

164.00€
A301-122A 100 µl -

2 - 8 business days*

588.00€
 
Protein function: Involved in global genome nucleotide excision repair (GG-NER) by acting as... more
Product information "Anti-XPC"
Protein function: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA- binding activity. [The UniProt Consortium]
Keywords: Anti-XPC, Anti-p125, Anti-XPCC, Anti-DNA repair protein complementing XP-C cells, Anti-Xeroderma pigmentosum group C-complementing protein
Supplier: Bethyl Laboratories
Supplier-Nr: A301-122A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: dog, orangutan, monkey, gorilla, chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by A301-122A maps to a region between residue 890 and 940 of human xeroderma pigmentosum, complementation group C using the numbering given in entry NP_004619.2 (GeneID 7508).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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