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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
A301-122A-T | 10 µl (2 µg) | - |
2 - 8 business days* |
164.00€
|
|||
A301-122A | 100 µl | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Involved in global genome nucleotide excision repair (GG-NER) by acting as... more
Product information "Anti-XPC"
Protein function: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA- binding activity. [The UniProt Consortium]
Keywords: | Anti-XPC, Anti-p125, Anti-XPCC, Anti-DNA repair protein complementing XP-C cells, Anti-Xeroderma pigmentosum group C-complementing protein |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-122A |
Properties
Application: | WB, IP |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: dog, orangutan, monkey, gorilla, chimpanzee) |
Immunogen: | synthetic peptide. The epitope recognized by A301-122A maps to a region between residue 890 and 940 of human xeroderma pigmentosum, complementation group C using the numbering given in entry NP_004619.2 (GeneID 7508). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K10838 | Matching products |
UniProt ID : | Q01831 | Matching products |
Gene ID | GeneID 7508 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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