Anti-UTX

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-374A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A302-374A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Histone demethylase that specifically demethylates 'Lys- 27' of histone H3,... more

Close menu

Product information "Anti-UTX"

Protein function: Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code (PubMed:17851529, PubMed:17713478, PubMed:17761849). Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27' (PubMed:17851529, PubMed:17713478, PubMed:17761849). Plays a central role in regulation of posterior development, by regulating HOX gene expression (PubMed:17851529). Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A (PubMed:17761849). [The UniProt Consortium]

Keywords:	Anti-UTX, Anti-KDM6A, Anti-Histone demethylase UTX, Anti-Lysine-specific demethylase 6A, Anti-Ubiquitously-transcribed TPR protein on the X chromosome, Anti-Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-374A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat, bovine, dog, horse, rabbit, swine, panda, orangutan, rhesus monkey, gorilla, chimpanzee, west indian ocean coelacanth, sauropsida, primates, fat-tailed dwarf lemur, white-tufted-ear marmoset, booted macaque)
Immunogen:	synthetic peptide. The epitope recognized by A302-374A maps to a region between residue 700 and 750 of human ubiquitously transcribed tetratricopeptide repeat, X chromosome using the numbering given in entry NP_066963.1 (GeneID 7403).
Format:	Antigen Affinity Purified