27 products were found matching "T9161-08.100"!

TNFR1 is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. Induction of cytotoxicity and other functions are mediated largely via TNFR1. This antibody is an agonistic antibody. Applications: Suitable for use in ELISA, Western Blot and Immunoprecipitation. Other...

Applications: , Suitable for use in Flow Cytometry, Immunohistochemistry and Functional Studies. Other applications have not been tested. , Recommended Dilutions: Immunohistochemistry (Frozen): 1:150 , Functional Studies: Neutralizes TNF-induced cytotoxicity on 4937 MCF-7, HeLa, and L929 cells, TNF-induced MHC...

Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA:...

Tumor necrosis factor receptor 1 (TNFR1), a potent cytokine, elicits a broad spectrum of biologic responses which are mediated by binding to a cell surface receptor. Its gene is located on 12p13. The coding region and the 3-prime untranslated region of TNFR1 are distributed over 10 exons. There are 2 different...

Tumor necrosis factor alpha (TNFalpha), also known as cachectin, is a 17.5kD, 157 amino acid member of the TNF superfamily of cytokines that is a potent lymphoid factor with effects on a wide range of target cells. Active TNFalpha is produced in both soluble and membrane-anchored trimers by macrophages, NK cells,...

TNF-R I is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. Induction of cytotoxicity and other functions are mediated largely via TNF-RI. Applications: Suitable for use in ELISA, Western Blot, Flow Cytometry and Immunoprecipitation. Other applications have not...

Tumor necrosis factor receptor 1 (TNF Receptor 1) binds cytokines TNF-alpha and TNF-beta resulting in the activation of pathways involved in both cell survival and apoptosis. TNF Receptor 1 contains an extracellular death domain that binds to the death domain adaptor protein TRADD and triggers the activation of...

TNF receptor I (TNF RI), also known as the p55 TNF receptor or CD120a, is a member of the TNF receptor superfamily. It has a molecular weight of 55kD and contains 4 extracellular cysteine-rich domains and an intracytoplasmic death domain of 80 aa, which can trigger apoptosis. Mouse and human TNF RI share 64% aa...

Tumor necrosis factor (TNF) induced signaling is mediated through association of TNF receptor (TNFR) with adaptor proteins, such as TNF receptor associated proteins (TRAFs). TRAFs form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily (e.g....

TNF-R2 is present on most cell types and is considered to be an important co-stimulator together with TNF-R1 in cellular responses to TNF-alpha, in particular the transmembrane form of TNF-alpha. A dominant role of TNF-R2 has been shown in thymocyte activation by TNF-alpha. TNF-alpha activates inflammatory...

TNF-RII is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. TNF-RII molecule is shown to be responsible for stimulation of activated T-lymphocytes by TNF-alpha. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry (frozen), Immunoprecipitation,...

Tumor Necrosis Factor Receptor Type 2 is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. The Tumor Necrosis Factor Receptor Type 2 molecule is shown to be responsible for stimulation of activated T-lymphocytes by TNF-alpha. Applications: Suitable for use in...