- Search results for 142577.50
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8 products were found matching "142577.50"!
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Item number: ABE-35-1427-50
Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia Protein function: Receptor tyrosine kinase binding ligands of the EGF family...
Keywords: | Anti-ERBB, EC=2.7.10.1, Anti-Proto-oncogene c-ErbB-1, Anti-Epidermal growth factor receptor, Anti-Receptor... |
Application: | ICC/IF, IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
574.00€
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Item number: Cay14577-50
Riluzole is a benzothiazole derivative with anti-excitotoxic effects that acts by blocking the presynaptic release of glutamate, indirectly antagonizing glutamate receptors, and inactivating neuronal voltage-gated Na+ channels (ED50 = 2.3 µM). Riluzole suppresses glutamate-induced seizures in rats at an ED50 value...
Keywords: | PK 26124, 6-(trifluoromethoxy)-2-benzothiazolamine, monohydrochloride |
CAS | 850608-87-6 |
MW: | 270.7 D |
From 50.00€
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Item number: ABE-35-1425-50
Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-a and amphiregulin. Protein function: Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently...
Keywords: | Anti-HER2, Anti-ERBB2, Anti-CD340, Anti-MLN 19, Anti-p185erbB2, EC=2.7.10.1, Anti-Proto-oncogene Neu, Anti-Proto-oncogene... |
Application: | WB, IHC, IF |
Host: | Rabbit |
Species reactivity: | human |
574.00€
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Item number: ABE-35-1577-50
NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing...
Keywords: | Anti-NFKB1, Polyclonal Antibody to NFkB-p105/p50 (Ab-932) |
Application: | WB, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
574.00€
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Item number: BOT-BNUM2477-50
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or...
Keywords: | MMP9 (Matrix Metalloproteinase 9)(MMP9/2477), 1mg/mL, |
Application: | IHC (paraffin) (verif.) |
565.00€
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Item number: BOT-BNUM1475-50
Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the transcriptional...
Keywords: | Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), 1mg/mL, |
Application: | WB (verif.) |
565.00€
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Item number: Cay17257-50
VER-155008 is an adenosine-derived inhibitor of heat shock protein 70 (Hsp70, IC50 = 0.5 µM) that is selective over Hsp90. It targets the nucleotide-binding domain (NBD) of Hsp70 and similarly binds the NBDs of Hsp70 cognates Hsc70 (Ki = 10 µM) and glucose-regulated protein 78 (Grp78, KD = 80 nM). VER-155008...
Keywords: | 5'-O-[(4-cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine |
Application: | HSP70 inhibitor |
CAS | 1134156-31-2 |
MW: | 556.4 D |
From 125.00€
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Item number: ABE-35-1475-50
Converts transient diacylglycerol. (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-kappa-B. Protein function: Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological...
Keywords: | Anti-PKD, Anti-PRKD1, Anti-nPKC-D1, Anti-nPKC-mu, EC=2.7.11.13, Anti-Protein kinase D, Anti-Protein kinase C mu type,... |
Application: | WB, IF |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
574.00€
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