Thymidine phosphorylase (TP) is a platelet-derived endothelial cell growth factor (PD-ECGF) that catalyzes the formation of thymine and 2-deoxy-D-ribose-1-phosphate from thymidine and orthophosphate (1). This intracellular enzyme is capable of both promoting angio-genesis and inhibiting apoptosis. Thymidine...

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for...

CD4, also known as L3T4, T4, and W3/25, is an ~55kD type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes. It is a standard phenotype marker for the identification of T cell populations. Mature rat CD4 consists of a 367aa extracellular region containing...

THSD1 (thrombospondin type 1 domain-containing protein 1, also TMTSP) is a 90-100kD type I transmembrane protein that is reminiscent of Unc5h proteins. It is expressed on embryonic endothelial and hematopoietic stem cells, and may be involved in cell-cell interactions. Mature human THSD1 contains a 388aa...

This monoclonal antibody recognizes the mouse protein TMTSP also known as THSD1, thrombospondin type-1 domain-containing protein, and transmembrane molecule with thrombospondin module. Mouse TMTSP has a predicted molecular weight of approximately 95kD. TMTSP is a single pass, Type I transmembrane receptor that...