Anti-TSC2

Anti-TSC2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A300-526A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A300-526A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or... more
Product information "Anti-TSC2"
Protein function: In complex with TSC1, this tumor suppressor inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Acts as a GTPase-activating protein (GAP) for the small GTPase RHEB, a direct activator of the protein kinase activity of mTORC1. May also play a role in microtubule-mediated protein transport. Also stimulates the intrinsic GTPase activity of the Ras-related proteins RAP1A and RAB5. [The UniProt Consortium]
Keywords: Anti-TSC2, Anti-TSC4, Anti-Tuberin, Anti-Tuberous sclerosis 2 protein
Supplier: Bethyl Laboratories
Supplier-Nr: A300-526A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, rat)
Immunogen: synthetic peptide. The epitope recognized by A300-526A maps to a region between residues 1 and 50 of human Tuberous Sclerosis 2 using the numbering given in Swiss-Prot entry P49815 (GeneID 7249).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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