A TRAF-interacting protein that specifically associates with TRAF6. T6BP shares an overall 50% identity and 59% similarity to a recently identified chicken protein MDP62, which has been implicated in promoting neurite outgrowth. T6BP-TRAF6 complex formation is dependent on the presence of the IL-1...

Tumor necrosis factor (TNF) induced signaling is mediated through association of TNF receptor (TNFR) with adaptor proteins, such as TNF receptor associated proteins (TRAFs). TRAFs form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily (e.g....

Applications: , Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Cellular Localization: Colocalizes with MAP3K3 to vesicle like structures throughout the cytoplasm. , Storage and Stability:, May be stored at 4°C for...

Neuropeptide Y (NPY), a 36 amino acid peptide amide, is a major regulatory neuropeptide widely distributed in the mammalian central (CNS) and peripheral nervous systems (PNS). NPY belongs to the pancreatic polypeptide family of peptides which are characterized by a common tertiary structure (1,2). Within this...