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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay10873-1 | 1 each | - |
6 - 10 business days* |
465.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Tumor necrosis factor (TNF)-induced signaling is mediated through association of TNF receptor... more
Product information "Anti-TRAF5 (Clone 55A219)"
Tumor necrosis factor (TNF)-induced signaling is mediated through association of TNF receptor (TNFR) with adaptor proteins, such as TNF receptor-associated factors (TRAFs). TRAFs form a family of cytoplasmic adapter proteins that mediate signal transduction from many members of the TNF-receptor superfamily (e.g., RANK, CD30, CD40, etc.) and the interleukin-1 receptor. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. Recent molecular cloning studies have led to identification of seven TRAFs (TRAF1-TRAF7). Human TRAF5 is a 557-amino acid protein. TRAF5 is implicated in NF-kB and c-Jun NH(2)-terminal kinase/stress-activated protein kinase activation by members of the TNF receptor superfamily, including CD27, CD30, CD40, and lymphotoxin-beta receptor. Targeted disruption of TRAF5 gene causes defects in CD40-CD27 mediated lymphocyte activation.Immunogen: fusion protein corresponding to amino acids 77-186 of human TRAF5. Clone Designation: 55A219. Formulation: (Request formulation change), 100 µg of protein G-purified IgG in 200 µl PBS containing 0.05% BSA and 0.05% sodium azide. Host: Mouse. Applications: WB. Origin: Animal/Mouse.
Keywords: | Anti-RNF84, Anti-TRAF5, Anti-RING finger protein 84, Anti-TNF receptor-associated factor 5 |
Supplier: | Cayman Chemical |
Supplier-Nr: | 10873 |
Properties
Application: | WB |
Antibody Type: | Monoclonal |
Clone: | 55A219 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse |
Immunogen: | fusion protein corresponding to amino acids 77-186 of human TRAF5 |
Format: | Purified |
Database Information
KEGG ID : | K09849 | Matching products |
UniProt ID : | O00463 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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