Anti-Sp1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A300-134A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A300-134A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Transcription factor that can activate or repress transcription in response to... more
Product information "Anti-Sp1"
Protein function: Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR- alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression. Isoform 3 is a stronger activator of transcription than isoform 1. Positively regulates the transcription of the core clock component ARNTL/BMAL1. [The UniProt Consortium]
Keywords: Anti-SP1, Anti-TSFP1, Anti-Transcription factor Sp1
Supplier: Bethyl Laboratories
Supplier-Nr: A300-134A

Properties

Application: WB, IP, IHC, ChIP-Seq
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: X. laevis, X. tropicalis, chicken, goat, bovine, dog, horse, rabbit, pig, panda, orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, african elephant, northern white-cheeked gibbon)
Immunogen: synthetic peptide. The epitope recognized by A300-134A maps to a region between residue 750 and the C-terminus (residue 785) using the numbering given in entry XP_028606.4 (GeneID 6667).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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