Anti-STIM1

Anti-STIM1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-414A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A303-414A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx... more
Product information "Anti-STIM1"
Protein function: Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores (PubMed:15866891, PubMed:16005298, PubMed:16208375, PubMed:16537481, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:18854159, PubMed:19249086, PubMed:22464749, PubMed:24069340, PubMed:24351972, PubMed:24591628, PubMed:26322679, PubMed:25326555). Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release- activated Ca(2+) (CRAC) channel subunit ORAI1 (PubMed:16208375, PubMed:16537481). Involved in enamel formation (PubMed:24621671). Activated following interaction with TMEM110/STIMATE, leading to promote STIM1 conformational switch (PubMed:26322679). [The UniProt Consortium]
Keywords: Anti-STIM1, Anti-Stromal interaction molecule 1
Supplier: Bethyl Laboratories
Supplier-Nr: A303-414A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, rat, bovine)
Immunogen: synthetic peptide. The epitope recognized by A303-414A maps to a region between residue 635 and 685 of human Stromal Interaction Molecule 1 using the numbering given in entry NP_003147.2 (GeneID 6786).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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