16 products were found matching "Cay10838-100"!

JWH 309 is a synthetic cannabinoid (CB) that displays high affinities for both the central CB1 receptor (Ki = 41 nM) and the peripheral CB2 receptor (Ki = 49 nM). The physiological and toxicological properties of this compound have not been examined. This product is intended for forensic and research...

Mn(III) protoporphyrin IX chloride is a metalloporphyrin. It induces mRNA expression of the genes encoding delta-aminolevulinate synthase and heme oxygenase (HO), enzymes that catalyze the rate-limiting steps of heme biosynthesis and degradation, respectively, in chick embryo liver cells when used at a concentration...

alpha-Fetoprotein is a glycoprotein and member of the albuminoid gene family and is involved in extracellular transport, cell proliferation, and the immune response. It is composed of a single polypeptide chain with three domains that form a V shape, the inside of which comprises the ligand-binding domain, and...

Embelin is a benzoquinone that has been found in E. ribes and has diverse biological activities. It inhibits viral replication of the influenza A subtype H1N1 and the influenza B subtype Victoria-like in MDCK cells (IC50s = 0.3 and 0.2 µM, respectively). It is also an inhibitor of X-linked inhibitor of apoptosis...

Decanoic acid is a medium-chain saturated fatty acid. It is a non-competitive antagonist at AMPA receptors that selectively reduces glutamate-induced currents in Xenopus oocytes expressing GluA2 and GluA3 subunit-containing AMPA receptors (IC50 = 0.52 mM) over those expressing GluA1 (IC50 = 2.09 mM) or GluA1 and...

(±)12-HpETE is one of the six monohydroperoxy fatty acids produced by the non-enzymatic oxidation of arachidonic acid (Cay-90010) and consists of an equal mixture of the R and S isomers. Reduction of the hydroperoxide yields the more stable hydroxyl fatty acid (±)12-HETE (Cay-34550). The biological activity of...

Naringenin-7-O-beta-D-glucuronide is a metabolite of the flavonoid naringenin (Cay-14173). It is formed from naringenin primarily by the UDP-glucuronosyltransferase (UGT) isoforms UGT1A1, UGT1A3, UGT1A6, and UGT1A9.Formal Name: 3,4-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-2H-1-benzopyran-7-yl,...

The transient receptor potential ankyrin 1 (TRPA1) ion channel integrates the nociception and transmission of diverse, potentially damaging and noxious stimuli, including cold, electrophilic compounds, divalent cations, and mechanical stimulation. TCS 5861528 is a selective TRPA1 blocker that antagonizes...

Prostaglandin K1 (PGK1) is a 9,11-diketo analog of PGE1 (Cay-13010) or PGD1 (Cay-12000). It is a PGE2 receptor subtype EP1 agonist that has 387-fold reduced potency compared to PGE2 (Cay-14010).Formal Name: 9,11-dioxo-15S-hydroxy-prost-13E-en-1-oic acid. CAS Number: 69413-73-6. Synonyms: PGK1. Molecular Formula:...

Montelukast is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 4.9 nM in HEK293 cell membranes expressing the human receptor). It is selective for CysLT1 over CysLT2 receptors (IC50 = >10,000 nM in COS-7 cell membranes expressing the human receptor). Montelukast inhibits bronchoconstriction induced by...

Leukotriene A4 (LTA4) hydrolase/aminopeptidase is a bifunctional zinc metalloenzyme that both catalyzes the synthesis of LTB4 (Cay-20110) from LTA4 and cleaves the chemotactic peptide Pro-Gly-Pro. SC-57461A is a potent, orally active inhibitor of LTA4 hydrolase that blocks ionophore-stimulated LTB4 synthesis in...

D-myo-Inositol-1,4-phosphate (Ins(1,4)P2) is a member of the inositol phosphate (InsP) molecular family that play critical roles as small, soluble second messengers in the transmission of cellular signals. The most studied InsP, Ins(1,4,5)P3 is a second messenger produced in cells by phospholipase C (PLC)-mediated...