Anti-SIRT1

Anti-SIRT1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BPS-25316 50 µg - -

3 - 15 business days*

706.00€
 
SirT1 (UniProtKB/Swiss Prot entry Q96EB6) is a NAD dependent deacetylase, which regulates... more
Product information "Anti-SIRT1"
SirT1 (UniProtKB/Swiss Prot entry Q96EB6) is a NAD dependent deacetylase, which regulates processes such as apoptosis and muscle differentiation by the deacetylation of key regulatory proteins. Deacetylation of lysine 382 of p53/TP53 by Sirt1 impairs its ability to induce the proapoptotic program and modulate cell senescence, whereas deacetylation of TAF1B represses rDNA transcription by the RNA polymerase I. SirT1 is also involved in HES1 and HEY2 mediated transcriptional repression and inhibits skeletal muscle differentiation by deacetylating PCAF and MYOD1. SirT1 is recruited to the nuclear bodies via its interaction with PML
Keywords: hSIR2, SIR2alpha, SIR2L1,
Supplier: BPS Bioscience
Supplier-Nr: 25316

Properties

Application: WB
Antibody Type: Monoclonal
Conjugate: No
Species reactivity: human
Immunogen: human SIRT1 (NAD dependent deacetylase sirtuin 1) using a synthetic peptide
Format: Purified

Handling & Safety

Storage: -80°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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