- Search results for Cay13780-500
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12 products were found matching "Cay13780-500"!
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Item number: Cay17803-500
Voriconazole-d3 is intended for use as an internal standard for the quantification of voriconazole (Cay-15633) by GC- or LC-MS. Voriconazole is a triazole antifungal agent and a derivative of fluconazole (Cay-11594). It is active against a variety of yeast and fungi, including clinical isolates of A. flavus, A....
Keywords: | VRC-d3, (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-4,4,4-d3-2-ol |
Application: | Internal standard |
MW: | 352.3 D |
From 240.00€
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Item number: Cay17380-500
Phosphatidylinositol 3-kinase (PI3K) catalyzes the phosphorylation of phosphatidylinositol at the 3 position to produce the second messengers phosphatidylinositol-3,4-bisphosphate (PtdIns-(3,4)-P2 and PtdIns-(3,4,5)-P3). Class 1 PI3Ks are composed of a p110 catalytic subunit, of which there are four isoforms...
Keywords: | 2-methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-(4-morpholinyl)-1H-benzimidazole-4-carboxylic acid |
Application: | PIK3CB inhibitor |
CAS | 1372540-25-4 |
MW: | 433.4 D |
From 60.00€
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Item number: Cay13580-500
HDMAPP is a metabolite of the microbial dioxyxylulose-phosphate pathway, which is analogous to the isopentenyl pyrophosphate pathway in mammals. It is a protease-resistant and phosphatase-sensitive pyrophosphate produced by bacteria and plants. HDMAPP is a non-peptide ligand, also called a phosphoantigen, that binds...
Keywords: | HMBPP, mono[(2E)-hydroxy-3-methyl-2-butenyl] ester diphosphoric acid, triammonium salt |
Application: | Microbial deoxyxylulose-phosphate pathway metabolite, TCR ligand |
CAS | 443892-56-6 |
MW: | 313.2 D |
From 102.00€
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Item number: Cay13870-50
Pyroxamide is an inhibitor of histone deacetylases (HDACs), including HDAC1 (IC50 = 0.1-0.2 µM). It induces growth suppression and cell death of certain types of cancer cells in culture.Formal Name: N1-hydroxy-N8-3-pyridinyl-octanediamide. CAS Number: 382180-17-8. Molecular Formula: C13H19N3O3. Formula Weight:...
Keywords: | N1-hydroxy-N8-3-pyridinyl-octanediamide |
Application: | Histone deacetylases Inhibitor |
CAS | 382180-17-8 |
MW: | 265.3 D |
From 82.00€
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Item number: Cay30780-50
666-15 is an inhibitor of gene transcription mediated by cAMP-response-element-binding protein (CREB, IC50 = 81 nM in a cell-based reporter assay). It inhibits the growth of A549, MCF-7, MDA-MB-231, and MDA-MB-468 cells (GI50s = 0.47, 0.31, 0.073, and 0.046 µM, respectively). 666-15 (10 mg/kg per day, five days per...
Keywords: | Compound 3i,... |
Application: | CREB-mediated gene transcription inhibitor |
CAS | 1433286-70-4 |
MW: | 620.5 D |
From 205.00€
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Item number: Cay37080-50
Transferrin receptor (TfR1), also known as CD71, is a homodimeric transmembrane receptor for transferrin (Cay-32030) that facilitates iron delivery into cells and is encoded by TFRC in humans. It is composed of two TfR1 monomers, each containing a cytoplasmic tail, an internalization motif, a membrane-spanning...
Keywords: | Anti-TR, Anti-TfR, Anti-CD71, Anti-Tfrc, Anti-TfR1, Anti-Trfr, Anti-Transferrin receptor protein 1 |
Application: | IHC |
Host: | Rabbit |
Species reactivity: | mouse |
From 176.00€
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Item number: Cay16835-500
Prostaglandin E2 (PGE2) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a Gs protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10580 is an 8-aza-9-oxo-15-hydroxy saturated analog of PGE2. It...
Keywords: | 2-(3-hydroxyoctyl)-5-oxo-1-pyrrolidineheptanoic acid |
Application: | EP4 receptor activator |
CAS | 64054-40-6 |
MW: | 341.5 D |
From 96.00€
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Item number: Cay13780-1
Diverse signal transduction pathways impinging on the N-terminal tails of histones lead to a number of post-translational modifications including acetylation, phosphorylation, poly (ADP-ribosylation), ubiquitination, and methylation. These modifications play critical roles in regulating chromatin structure and gene...
Keywords: | Anti-SETD7, Anti-SET7/9, Anti-SET7/9, Anti-KIAA1717, Anti-H3-K4-HMTase SETD7, Anti-H3-K4-HMTase SETD7, Anti-Lysine... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse |
422.00€
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Item number: Cay13740-500
Butaprost, a structural analog of PGE2, is a selective agonist for the EP2 receptor subtype. EP2 receptors are expressed on human neutrophils and on respiratory, vascular, and uterine smooth muscle. Butaprost binds with about 1/10 the affinity of PGE2 to the recombinant murine EP2 receptor, and does not bind...
Keywords: | 15-deoxy-16S-hydroxy-17-cyclobutyl PGE1 methyl ester, TR 4979,... |
Application: | EP2 receptor agonist |
CAS | 69685-22-9 |
MW: | 408.6 D |
From 115.00€
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Item number: Cay13680-500
15-keto PGE1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH. It has greatly diminished biological activity compared to PGE1.Formal Name: (11alpha,13E)-11-hydroxy-9,15-dioxo-prost-13-en-1-oic acid. CAS Number: 22973-19-9. Synonyms: 15-keto PGE1. Molecular Formula: C20H32O5. Formula Weight: 352.5....
Keywords: | 15-keto PGE1, 9,15-dioxo-11alpha-hydroxy-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 22973-19-9 |
MW: | 352.5 D |
From 88.00€
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Item number: Cay13730-500
15(S)-15-methyl Prostaglandin E1 (15(S)-15-methyl PGE1) is a metabolically stable synthetic analog of PGE1 (Cay-13010). In sharp contrast to the bronchodilatory effects of PGE1, 15(S)-15-methyl PGE1 is a weak constrictor of human respiratory tract smooth muscle.Formal Name:...
Keywords: | 15(S)-15-methyl PGE1, 9-oxo-11alpha,15S-dihydroxy-15-methyl-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 35700-26-6 |
MW: | 368.5 D |
From 125.00€
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Item number: Cay13500-1
Histone deacetylase 7 (HDAC7) is a thymus-specific, intracellular transcription factor belonging to the class IIa HDAC family. Reports suggest that dephosphorylation and nuclear localization of HDAC7 is promoted by myosin phosphatase, thus regulating the repression of Nur77 and inhibition of apoptosis in CD4+/CD8+...
Keywords: | Histone Deacetylase 7 |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
485.00€
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