Anti-phospho-PTEN (Tyr315) (PTEN, MMAC1, TEP1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatas

Anti-phospho-PTEN (Tyr315) (PTEN, MMAC1, TEP1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatas
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040618.200 200 µl - -

3 - 19 business days*

728.00€
 
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at... more
Product information "Anti-phospho-PTEN (Tyr315) (PTEN, MMAC1, TEP1, Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatas"
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. Applications: Suitable for use in Dot Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Dot blot 1:500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-phospho-PTEN, Anti-phospho-MMAC1, EC=3.1.3.48, EC=3.1.3.16, EC=3.1.3.67, Anti-phospho-Phosphatase and tensin homolog, Anti-phospho-Mutated in multiple advanced cancers 1, Anti-phospho-Phosphatidylinositol 3,4
Supplier: United States Biological
Supplier-Nr: 040618

Properties

Application: ELISA, Dot Blot
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: PTEN Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y315 of human PTEN.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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