- Search results for A302-939A
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27 products were found matching "A302-939A"!
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Item number: A302-399A-T
Protein function: Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction...
Keywords: | Anti-TNKS, Anti-ARTD5, Anti-TANK1, Anti-TNKS-1, Anti-PARP5A, EC=2.4.2.30, Anti-Tankyrase-1, Anti-Tankyrase I, Anti-Poly... |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A302-969A
Protein function: Promotes ubiquitination of several tyrosine- phosphorylated Src substrates, including CDH1, CTTN and DOK1. Targets CDH1 for endocytosis and degradation. [The UniProt Consortium]
Keywords: | Anti-CBLL1, Anti-HAKAI, EC=2.3.2.27, Anti-c-Cbl-like protein 1, Anti-RING finger protein 188, Anti-E3 ubiquitin-protein... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A302-929A
Protein function: Hydrolase that can remove conjugated ubiquitin from proteins and therefore plays an important regulatory role at the level of protein turnover by preventing degradation. Converts both 'Lys-48' an 'Lys-63'-linked ubiquitin chains. Catalytic activity is enhanced in the M phase. Involved in cell...
Keywords: | Anti-USP8, Anti-hUBPy, Anti-KIAA0055, Anti-Ubiquitin thioesterase 8, Anti-Ubiquitin isopeptidase Y, Anti-Deubiquitinating... |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A302-949A-T
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal...
Keywords: | Anti-WWP1, Anti-AIP5, Anti-Tiul1, EC=2.3.2.26, Anti-WW domain-containing protein 1, Anti-Atrophin-1-interacting protein 5,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A302-979A-T
Protein function: May play a role in later stages of the processing of the pre-ribosomal particles leading to mature 60S ribosomal subunits. Has intrinsic ATPase activity. [The UniProt Consortium]
Keywords: | Anti-DDX21, Anti-DDX56, EC=3.6.4.13, Anti-DEAD box protein 56, Anti-DEAD box protein 21, Anti-Probable ATP-dependent RNA... |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A302-989A
Protein function: Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer (PubMed:24793695, PubMed:24793696). Required for localization of...
Keywords: | Anti-CCDC8, Anti-Coiled-coil domain-containing protein 8 |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A302-909A
Protein function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced...
Keywords: | Anti-EULIR, Anti-HECTD1, Anti-KIAA1131, Anti-E3 ligase for inhibin receptor, Anti-HECT domain-containing protein 1,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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Item number: A302-919A
Protein function: Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-...
Keywords: | Anti-DUBA, Anti-OTUD5, EC=3.4.19.12, Anti-Deubiquitinating enzyme A, Anti-OTU domain-containing protein 5 |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A302-959A
Protein function: Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional...
Keywords: | Anti-JUN, Anti-p39, Anti-AP1, Anti-Activator protein 1, Anti-Proto-oncogene c-Jun, Anti-Transcription factor AP-1,... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A302-999A
Protein function: Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1 (PubMed:25278552). [The UniProt Consortium]
Keywords: | Anti-ANKRD50, Anti-KIAA1223, Anti-Ankyrin repeat domain-containing protein 50 |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A301-939A
Protein function: Regulatory subunit of cyclin-dependent kinases that mediates activation of target kinases. Plays a role in transcriptional regulation via its role in regulating the phosphorylation of the C-terminal domain (CTD) of the large subunit of RNA polymerase II (POLR2A). [The UniProt Consortium]
Keywords: | Anti-CCNK, Anti-CPR4, Anti-Cyclin-K |
Application: | WB, IP, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 164.00€
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Item number: A302-539A
Protein function: Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other...
Keywords: | Anti-AFF4, Anti-AF5Q31, Anti-HSPC092, Anti-Protein AF-5q31, Anti-AF4/FMR2 family member 4, Anti-ALL1-fused gene from... |
Application: | WB, IP |
Host: | Rabbit |
Species reactivity: | human |
From 164.00€
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