Anti-PKM2

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-659A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A303-659A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from... more
Product information "Anti-PKM2"
Protein function: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. [The UniProt Consortium]
Keywords: Anti-p58, Anti-PKM, Anti-OIP3, Anti-OIP-3, Anti-CTHBP, Anti-THBP1, EC=2.7.1.40, Anti-Tumor M2-PK, Anti-Pyruvate kinase PKM, Anti-Pyruvate kinase 2/3, Anti-Opa-interacting protein 3, Anti-Pyruvate kinase muscle isozyme
Supplier: Bethyl Laboratories
Supplier-Nr: A303-659A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: orangutan)
Immunogen: Synthetic peptide. The epitope recognized by A303-659A maps to a region between residue 1 and 50 of human Pyruvate Kinase Isozymes M1/M2 using the numbering given in entry NP_002645.3 (GeneID 5315).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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