28 products were found matching "P4258-96.100"!

The platelet-derived growth factor (PDGF) family consists of four disulfide-linked homodimers and one heterodimer (PDGF-AB). These proteins regulate diverse cellular functions through interactions with PDGF Ra and Rb (1, 2). Mature PDGF-DD associates with PDGF Rb and triggers signaling through PDGF Rb homodimers and...

The proteins of the platelet derived growth factor (PDGF) family exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor a (PDGFRa) and PDGF receptor B (PDGFRb). PDGFra and...

Platelet-Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B. The PDGF protein has been implicated both directly as well as indirectly in several pathological states...

Platelet derived growth factor A chain), a disulphide-linked alpha-chain homodimer and member of the PDGF family, released from platelet alpha-granules following trauma/platelet activation. Naturally occurring active forms of PDGF exist as dimers of two alpha chains (AA), two beta chains (BB), or a combination of...

Applications:, Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C....

PDGFs are disulfide-linked dimers consisting of two 12.0-13.5kD polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs. (PDGF-AA, PDGF-BB and PDGF-AB) are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage...

The proteins of the PDGF family consist of several disulfide- bonded dimeric isoforms: PDGFAA, PDGF-AB, PDGF-BB, PDGF-CC and PDGF-DD, which bind in a distinct pattern to two highly related RTKs: PDGFR-a and PDGFR-b. PDGFR-a and PDGFR-b show 85% and 75% identity between the two intracellular kinase domains, but the...

Platelet-derived growth factor (PDGF) exerts its stimulatory effects on cell growth and motility by binding to two related protein tyrosine kinase receptors, which can associate as three dimer forms (alpha/ alpha, alpha/beta, beta/beta) with variable binding specificity for the PDGF ligands (1,2). The total number...

The proteins of the platelet derived growth factor (PDGF) family exist as several disulphide-bonded, dimeric isoforms that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor alpha (PDGFRa) and PDGF receptor beta (PDGFRb). PDGFRa and PDGFRb share 75%-85% sequence homology...

PDGF is a major serum mitogen that can exist as a homo- or heterodimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA, PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Whereas PDGF Ralpha binds all three PDGF...

PDGF is a major serum mitogen that can exist as a homo- or heterodimeric protein consisting of disulfide-linked PDGF-A and PDGF-B chains. The PDGF-AA, PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Whereas PDGF Ralpha binds all three PDGF...

Platelet-derived growth factor (PDGF) exerts its stimulatory effects on cell growth and motility by binding to two related protein tyrosine kinase receptors, which can associate as three dimer forms (alpha/alpha, alpha/beta, beta/beta) with variable binding specificity for the PDGF ligands (1,2). The total number of...