Anti-PBEF (IHC)

Anti-PBEF (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00011-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00011 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Catalyzes the condensation of nicotinamide with 5-... more
Product information "Anti-PBEF (IHC)"
Protein function: Catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression. [The UniProt Consortium]
Keywords: Anti-PBEF, Anti-NAMPT, Anti-Nampt, Anti-Visfatin, Anti-NAmPRTase, EC=2.4.2.12, Anti-Pre-B cell-enhancing factor, Anti-Pre-B-cell colony-enhancing factor 1, Anti-Nicotinamide phosphoribosyltransferase
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00011

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, rat, zebrafish, X. laevis, X. tropicalis, chicken, turkey, bovine, dog, horse, rabbit, guinea pig_10141, pig, panda)
Immunogen: synthetic peptide. The epitope recognized by IHC-00011maps to a region between residue 400 and 450 of human pre-B-cell colony enhancing factor using the numbering given in SwissProt entry P43490 (GeneID 10135).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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