4 products were found matching "Cay100002-500"!
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3-Deazaneplanocin A (hydrochloride)
Item number: Cay11102-500
The lysine methyltransferase EZH2 (KMT6), part of the polycomb repressive complex 2, catalyzes trimethylation of lysine 27 on histone H3 and is involved in proliferation and aggressive cell growth associated with neoplastic cells. 3-Deazaneplanocin A is a cyclopentenyl analog of 3-deazaadenosine, originally...
| Keywords: | 2,3-DMMC, 5R-(4-amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1S,2R-diol, monohydrochloride |
| CAS | 120964-45-6 |
| MW: | 298.7 D |
From 123.00€
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BIBF 1120
Item number: Cay11022-50
BIBF 1120 is an inhibitor of the receptor tyrosine kinases VEGFR, FGFR, and PDGFR (IC50s = 13-34, 37-610, 59, and 65 nM for VEGFR1-3, FGFR1-4, PDGFRalpha, and PDGFRbeta, respectively). It is selective for VEGFR, FGFR, and PDGFR over a panel of 33 kinases but does inhibit FLT3, LCK, LYN, and Src (IC50s = 16-156 nM)....
| Keywords: | Nintedanib,... |
| Application: | Receptor tyrosine kinase inhibitor |
| CAS | 656247-17-5 |
| MW: | 539.6 D |
From 60.00€
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F16
Item number: Cay10022-50
F16 is a small, cationic, lipophilic molecule which binds preferentially to mitochondrial membranes and disrupts their function. F16 was discovered in high throughput screens for tumor inhibitors, where it was found to induce apoptosis in HER-1/EGFR-expressing breast carcinoma cell lines. In addition to being a...
| Keywords: | 4-[(1E)-2-(1H-indol-3-yl)ethenyl]-1-methyl-pyridinium iodide |
| Application: | Antitumor agent, Apoptosis inducer |
| CAS | 36098-33-6 |
| MW: | 362.2 D |
From 19.00€
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Anti-Programmed Cell Death Protein 4 (C-Term)
Item number: Cay10250-1
Programmed cell death protein 4 (PDCD4) levels are elevated during apoptosis and absent in many cancer samples. Loss of PDCD4 expression is an important event in cancer cell progression whereas the restoration of PDCD4 protein can lower metalloproteinase activity and possible metastasis. The known isoforms of PDCD4...
| Keywords: | Anti-H731, Anti-PDCD4, Anti-Protein 197/15a, Anti-Protein 197/15a, Anti-Nuclear antigen H731-like, Anti-Nuclear antigen... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
422.00€
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