- Search results for Cay13718-100
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13 products were found matching "Cay13718-100"!
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Item number: Cay13710-1
15(R)-PGE1 is the "unnatural" C-15 stereoisomer of PGE1. It is essentially inactive biologically when compared to PGE1. It is a non-competitive inhibitor of 15-hydroxy PGDH with an IC50 of 189 µM.Formal Name: 9-oxo-11alpha,15R-dihydroxy-prost-13E-en-1-oic acid. CAS Number: 20897-91-0. Synonyms: 15(R)-PGE1, 15-epi...
Keywords: | 15(R)-PGE1, 15-epi PGE1, 9-oxo-11alpha,15R-dihydroxy-prost-13E-en-1-oic acid |
Application: | PGDH inhibitor |
CAS | 20897-91-0 |
MW: | 354.5 D |
From 97.00€
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Item number: Cay23718-100
Methimazole is an inhibitor of thyroid hormone synthesis. It is a substrate for thyroid peroxidase that traps oxidized iodide, preventing its use by thyroglobulin for thyroid hormone synthesis. Methimazole (0.4 mg/kg) inhibits the absorption of radiolabeled iodide by the thyroid gland in rats by 80.9%. It reduces...
Keywords: | NSC 38608, 1,3-dihydro-1-methyl-2H-imidazole-2-thione |
Application: | Thyroid hormone synthesis inhibitor, Thyroid peroxidase substrate |
CAS | 60-56-0 |
MW: | 114.2 D |
From 77.00€
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Item number: Cay10718-100
JWH 073 5-hydroxyindole metabolite-d7 (Cay-10718) is intended for use as an internal standard for the quantification of JWH 073 5-hydroxyindole metabolite (Cay-9000862) by GC- or LC-MS. JWH 073 is a mildly selective agonist of the central cannabinoid (CB1) receptor derived from the aminoalkylindole WIN 55,212-2. The...
Keywords: | (1-butyl-2,2,3,3,4,4,4-d7-5-hydroxy-1H-indol-3-yl)(naphthalen-1-yl)-methanone |
Application: | Analytical reference standard, GC-MS, LC-MS internal standard, Quantification |
CAS | 1630022-99-9 |
MW: | 350.5 D |
From 339.00€
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Item number: Cay17718-100
TC-E 5003 is an inhibitor of protein arginine methyltransferase 1 (PRMT1, IC50 = 1.5 µM for human PRMT1 in a methylation assay). It is selective for PRMT1 over PRMT4/CARM1 and SET7/9 methyltransferases, with less than 5% inhibition at a concentration of 50 µM for SET7/9. TC-E 5003 inhibits growth of MCF-7a breast...
Keywords: | NSC 30176, N,N'-(sulfonyldi-4,1-phenylene)bis[2-chloro]-acetamide |
CAS | 17328-16-4 |
MW: | 401.3 D |
From 60.00€
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Item number: Cay17138-10
alpha-Pyrrolidinopentiophenone (alpha-PVP, Cay-9001083) is an analog of pyrovalerone (Cay-10817), a psychoactive compound that is regulated as Schedule V in the United States. Pyrrolidinophenone-derived designer drugs, like alpha-PVP, are emerging drugs of interest. alpha-Pyrrolidinononanophenone (alpha-PNP) is a...
Keywords: | PV-10, alpha-PNP, 1-phenyl-2-(1-pyrrolidinyl)-1-nonanone, monohydrochloride |
Application: | Analytical reference standard, Novel alpha-PVP analog |
CAS | 2748414-29-9 |
MW: | 323.9 D |
From 291.00€
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Item number: Cay13178-10
The sirtuins (SIRTs) are a family of NAD+-dependent histone deacetylases involved in gene regulation that is relevant to, e.g., longevity, cancer, gene regulation, energy homeostasis, and apoptosis. Salermide is an inhibitor of SIRT1 and SIRT2, causing tumor-specific apoptotic cell death. In MOLT4 leukemia cells,...
Keywords: | N-[3-[[(2-hydroxy-1-naphthalenyl)methylene]amino]phenyl]-a-methyl-benzeneacetamide |
Application: | SIRT inhibitor |
CAS | 1105698-15-4 |
MW: | 394.5 D |
From 68.00€
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Item number: Cay13187-10
Most tissues have an endogenous pool of progenitor cells to draw from upon injury. The adult heart, however, contains a limited number of undifferentiated cells and techniques to replicate these cells from other pluripotent tissues have thus far been nonselective and inefficient. Cardiogenol C is a diaminopyrimidine...
Keywords: | 2-[[2-[(4-methoxyphenyl)amino]-4-pyrimidinyl]amino]-ethanol |
Application: | Differentiation of MHC-positive cardiomyocytes |
CAS | 671225-39-1 |
MW: | 296.8 D |
From 43.00€
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Item number: Cay31718-10
Bupivacaine (hydrochloride) (Cay-31718) is an analytical reference standard categorized as a local anesthetic. Formulations containing bupivacaine have been used as local anesthetics for surgery and dental procedures. This product is intended for use in analytical forensic applications. This product is also...
Keywords: | (±)-1-butyl-2',6'-Pipecoloxylidide, AH 2250, 1-butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide, monohydrochloride |
Application: | Analytical reference standard, local anesthetic |
CAS | 18010-40-7 |
MW: | 324.9 D |
From 43.00€
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Item number: Cay13713-100
Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. They are present in the membranes that surround all biological cells and their main function is to...
Keywords: | Anti-KCNQ4, Anti-KQT-like 4, Anti-Potassium channel subunit alpha KvLQT4, Anti-Voltage-gated potassium channel subunit... |
Application: | ICC, IP, WB |
Host: | Mouse |
Species reactivity: | human |
530.00€
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Item number: Cay13100-100
A common metabolic pathway for several prostaglandins (PGs), including prostaglandin D2 (PGD2), involves the reduction of the double bond between C-13 and C-14 and oxidation of the hydroxyl group at C-15, producing 13,14-dihydro-15-keto PGs. The removal of four carbons at the alpha-terminus and oxidation of the...
Keywords: | 9alpha-hydroxy-11,15-dioxo-2,3,4,5-tetranor-prostanoic acid |
Application: | Metabolic studies |
CAS | 1204116-69-7 |
MW: | 298.4 D |
From 141.00€
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Item number: Cay13108-10
VX-702 is a third generation inhibitor of p38 mitogen-activated protein (MAP) kinases, binding to both p38alpha and p38beta (Kd = 3.7 and 17 nM, respectively) in an ATP-competitive fashion. It inhibits IL-6, IL-1beta, and TNF-alpha production in LPS-primed blood with IC50 values of 59, 122, and 99 ng/ml,...
Keywords: | 6-[(aminocarbonyl)(2,6-difluorophenyl)amino]-2-(2,4-difluorophenyl)-3-pyridinecarboxamide |
Application: | p38 MAP kinase inhibitor |
CAS | 745833-23-2 |
MW: | 404.3 D |
From 34.00€
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Item number: Cay17108-10
Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity. Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to...
Keywords: | 9Z-octadecenoic acid, 11-carboxy-1-hexylundecyl ester |
Application: | Branched fatty acid ester of hydroxy fatty acid (FAHFA) |
CAS | 101901-73-9 |
MW: | 564.9 D |
From 84.00€
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