Anti-NS5B (HCV), blocking, clone 5B-12B

Anti-NS5B (HCV), blocking, clone 5B-12B
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-20B-0003-C100 100 µg -

3 - 9 business days*

374.00€
 
Recognizes HCV NS5B from HCV genotype 1 (epitope mapped to NS5B aa 139-392). Does not react with... more
Product information "Anti-NS5B (HCV), blocking, clone 5B-12B"
Recognizes HCV NS5B from HCV genotype 1 (epitope mapped to NS5B aa 139-392). Does not react with genotype 2. Liquid. In PBS containing 0.02% sodium azide. The NS3 serine protease, in association with NS4A, is responsible for the cleavages of the Hepatitis C virus protease complexes NS3-NS4A, NS4A-NS4B, NS4B-NS5A and NS5A-NS5B. NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Hepatitis C virus protease NS3-NS4A colocalizes with IPS-1/VISA/MAVS/Cardif in the mitochondrial membrane and has been shown to cleave the TLR3 adapter TRIF and Cardif to eliminate the antiviral signaling pathways. NS3-NS4A represents an important target for anti-HCV drugs.
Keywords: Nonstructural Protein 5B
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-20B-0003

Properties

Application: FA (Blocking), ICC, IP
Antibody Type: Monoclonal
Clone: 5B-12B7
Conjugate: No
Host: Mouse
Species reactivity: HCV
Immunogen: Recombinant hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase.
Format: Purified

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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