Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in...

CMG-2, also known as anthrax toxin receptor 2 (ANTXR2) is a 45kD type I membrane protein with a von Willebrand factor A/integrin-like inserted domain in its extracellular region. CMG-2 binds laminin and collagen type IV. It also interacts with the protective antigen (PA) subunit of anthrax toxin. Applications:...

Necessary for cellular interactions with laminin and the extracellular matrix. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:16,000, Western Blot: 0.3-1ug/ml, human, mouse and rat kidney lysates observed on ~60kD bands, Optimal dilutions to be...