12 products were found matching "Cay16651"!

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SGI-1027
SGI-1027

Item number: Cay11165-1

SGI-1027 is an inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 µM, respectively, with Poly(dI-dC) as the substrate). It has been shown to cause the degradation of DNMT1 and to reactivate silenced tumor suppressor genes by reducing CpG island hypermethylation.Formal Name:...
Keywords: DNA Methyltransferase Inhibitor II, N-[4-[(2-amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)-benzamide
Application: DNMT1 / DNMT3A / DNMT3B inhibitor
CAS 1020149-73-8
MW: 461.5 D
From 50.00€ *
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Goat Anti-Rabbit IgG:SureLight(TM) R-PE
Goat Anti-Rabbit IgG:SureLight(TM) R-PE

Item number: Cay16655-1

Goat anti-Rabbit IgG conjugated to SureLight(TM) R-PE Antibody: Goat polyclonal anti-Rabbit IgG (minimally reactive toward mouse, bovine serum proteins) Dye: SureLight(TM) R-phycoerythrin (R-PE) Excitation max. lambda: 565>498 nm Emission max. lambda: 578 nm Uses: Flow cytometry, fluorescence-activated cell sorting,...
Application: Cell based assays, FC
Host: Goat
Species reactivity: rabbit
From 148.00€ *
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Goat Anti-Mouse IgM:SureLight(TM) R-PE
Goat Anti-Mouse IgM:SureLight(TM) R-PE

Item number: Cay16651-100

Goat anti-Mouse IgM conjugated to SureLight(TM) R-PE Antibody: Goat polyclonal anti-Mouse IgM Dye: SureLight(TM) R-phycoerythrin Excitation max. lambda: 565>498 nm Emission max. lambda: 578 nm Uses: Flow cytometry, Fluorescence-activated cell sorting, Luminex, and Protein MicroarraysEmission: 578 nm. Excitation:...
Application: Cell based assays, FC
Host: Goat
Species reactivity: mouse
293.00€ *
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4-Methylumbelliferyl-alpha-D-Galactopyranoside
4-Methylumbelliferyl-alpha-D-Galactopyranoside

Item number: Cay16551-25

4-Methylumbelliferyl-alpha-D-galactopyranoside (4-MU-alpha-Gal) is a fluorogenic substrate of alpha-galactosidase. In addition to its use in characterizing novel alpha-galactosidases, 4-MU-alpha-Gal is used in assays to evaluate deficiency in alpha-galactosidase activity related to Fabry disease. Hydrolysis of...
Keywords: 4-MU-alpha-Gal, MU-alpha-Gal, 7-(alpha-D-galactopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one
Application: Fluorogenic alpha-galactosidase substrate
CAS 38597-12-5
MW: 338.3 D
From 43.00€ *
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Rabbit Anti-Goat IgG:SureLight(TM) R-PE
Rabbit Anti-Goat IgG:SureLight(TM) R-PE

Item number: Cay16656-1

Rabbit anti-Goat IgG, secondary antibody, conjugated to SureLight(R) R-PE Antibody: Rabbit polyclonal anti-goat IgG Dye: SureLight(R) R-phycoerythrin Excitation max. lambda: 565>498 nm Emission max. lambda: 578 nm Uses: Flow cytometry, fluorescence-activated cell sorting, and protein microarraysEmission: 578 nm....
Application: Cell based assays, FC
Host: Rabbit
Species reactivity: goat
474.00€ *
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MC 1568
MC 1568

Item number: Cay16265-1

While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which includes HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. MC 1568 is a selective inhibitor of...
Keywords: (2E)-3-[5-[(1E)-3-(3-fluorophenyl)-3-oxo-1-propen-1-yl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide
Application: Selective class IIa HDAC inhibitor
CAS 852475-26-4
MW: 314.3 D
From 43.00€ *
Review
(+)-Cloprostenol
(+)-Cloprostenol

Item number: Cay16765-1

(+)-Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent...
Keywords: (+)-16-m-chlorophenoxy tetranor PGF2alpha, (+)-16-m-chlorophenoxy tetranor Prostaglandin F2alpha, D-Cloprostenol,...
Application: FP receptor agonist
CAS 54276-21-0
MW: 424.9 D
From 97.00€ *
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U-51605
U-51605

Item number: Cay16465-1

U-51605 is a stable analog of the endoperoxide prostaglandin H2 (PGH2). It is an inhibitor of both prostacyclin (PGI) and thromboxane (TX) synthases with more selectivity towards PGI synthase. U-51605 is also a partial agonist at TP receptors. In human foreskin fibroblasts, U-51605 inhibits PGI synthase at a...
Keywords: 9alpha,11alpha-azoprosta-5Z,13E-dien-1-oic acid
Application: PGI synthase inhibitor
CAS 64192-56-9
MW: 332.5 D
From 58.00€ *
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4-Methylumbelliferyl Phosphate
4-Methylumbelliferyl Phosphate

Item number: Cay16645-1

4-Methylumbelliferyl Phosphate (4-MUP) is a fluorogenic substrate for phosphatases, including acid and alkaline phosphatases. It is converted to the fluorescent product 4-methylumbelliferone (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at...
Keywords: 4-Methylumbelliferone Phosphate, 4-MU Phosphate, 4-MUP, 7-hydroxy-4-Methylcoumarin Phosphate,...
Application: Phosphatase fluorogenic substrate
CAS 3368-04-5
MW: 256.2 D
From 39.00€ *
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Octyl-alpha-hydroxyglutarate
Octyl-alpha-hydroxyglutarate

Item number: Cay16365-1

alpha-Hydroxyglutaric acid (2-HG, Cay-16374) is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases. Mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder. Recent studies have found that mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2,...
Keywords: Octyl-2-HG, 2-hydroxy-pentanedioic acid, 1-octyl ester
Application: Cell-permeable 2-HG derivative
CAS 2097068-39-6
MW: 260.3 D
From 73.00€ *
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Lumula
Lumula

Item number: Cay16685-1

Lumula is a hybrid eicosanoid analog that incorporates the docosanoid and prostamide features of unoprostone (Cay-16680) and bimatoprost (17-phenyl trinor Prostaglandin F2alpha ethyl amide, Cay-16820), respectively, prostaglandin analogs that lack potency at the prostanoid FP receptor. Based on classical...
Keywords: Maxeyprost, Unoprostone N-ethyl amide, N-ethyl-9alpha,11alpha-dihydroxy-15-oxo-20a,20b-dihomoprost-5-en-1-amide
Application: Bioactive lipid assays
CAS 511229-72-4
MW: 409.6 D
From 319.00€ *
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ARN1203
ARN1203

Item number: Cay16065-1

Arachidonoyl ethanolamide (AEA, Cay-90050), also known as anandamide, is an endogenous ligand of the cannabinoid receptors. AEA is metabolized by fatty acid amide hydrolase (FAAH) to give arachidonic acid (Cay-90010) and ethanolamine. ARN1203 is a fluorinated analog of AEA that serves as a substrate of FAAH (Km = 29...
Keywords: N-(3-fluoro-2-hydroxypropyl)-5Z,8Z,11Z,14Z-eicosatetraenamide
Application: FAAH substrate
CAS 1428445-15-1
MW: 379.6 D
From 43.00€ *
Review