- Search results for Cay16651
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12 products were found matching "Cay16651"!
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Item number: Cay11165-1
SGI-1027 is an inhibitor of the DNA methyltransferases DNMT1, DNMT3A, and DNMT3B (IC50s = 12.5, 8, and 7.5 µM, respectively, with Poly(dI-dC) as the substrate). It has been shown to cause the degradation of DNMT1 and to reactivate silenced tumor suppressor genes by reducing CpG island hypermethylation.Formal Name:...
Keywords: | DNA Methyltransferase Inhibitor II, N-[4-[(2-amino-6-methyl-4-pyrimidinyl)amino]phenyl]-4-(4-quinolinylamino)-benzamide |
Application: | DNMT1 / DNMT3A / DNMT3B inhibitor |
CAS | 1020149-73-8 |
MW: | 461.5 D |
From 50.00€
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Item number: Cay16655-1
Goat anti-Rabbit IgG conjugated to SureLight(TM) R-PE Antibody: Goat polyclonal anti-Rabbit IgG (minimally reactive toward mouse, bovine serum proteins) Dye: SureLight(TM) R-phycoerythrin (R-PE) Excitation max. lambda: 565>498 nm Emission max. lambda: 578 nm Uses: Flow cytometry, fluorescence-activated cell sorting,...
Application: | Cell based assays, FC |
Host: | Goat |
Species reactivity: | rabbit |
From 148.00€
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Item number: Cay16651-100
Goat anti-Mouse IgM conjugated to SureLight(TM) R-PE Antibody: Goat polyclonal anti-Mouse IgM Dye: SureLight(TM) R-phycoerythrin Excitation max. lambda: 565>498 nm Emission max. lambda: 578 nm Uses: Flow cytometry, Fluorescence-activated cell sorting, Luminex, and Protein MicroarraysEmission: 578 nm. Excitation:...
Application: | Cell based assays, FC |
Host: | Goat |
Species reactivity: | mouse |
293.00€
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Item number: Cay16551-25
4-Methylumbelliferyl-alpha-D-galactopyranoside (4-MU-alpha-Gal) is a fluorogenic substrate of alpha-galactosidase. In addition to its use in characterizing novel alpha-galactosidases, 4-MU-alpha-Gal is used in assays to evaluate deficiency in alpha-galactosidase activity related to Fabry disease. Hydrolysis of...
Keywords: | 4-MU-alpha-Gal, MU-alpha-Gal, 7-(alpha-D-galactopyranosyloxy)-4-methyl-2H-1-benzopyran-2-one |
Application: | Fluorogenic alpha-galactosidase substrate |
CAS | 38597-12-5 |
MW: | 338.3 D |
From 43.00€
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Item number: Cay16656-1
Rabbit anti-Goat IgG, secondary antibody, conjugated to SureLight(R) R-PE Antibody: Rabbit polyclonal anti-goat IgG Dye: SureLight(R) R-phycoerythrin Excitation max. lambda: 565>498 nm Emission max. lambda: 578 nm Uses: Flow cytometry, fluorescence-activated cell sorting, and protein microarraysEmission: 578 nm....
Application: | Cell based assays, FC |
Host: | Rabbit |
Species reactivity: | goat |
474.00€
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Item number: Cay16265-1
While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which includes HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. MC 1568 is a selective inhibitor of...
Keywords: | (2E)-3-[5-[(1E)-3-(3-fluorophenyl)-3-oxo-1-propen-1-yl]-1-methyl-1H-pyrrol-2-yl]-N-hydroxy-2-propenamide |
Application: | Selective class IIa HDAC inhibitor |
CAS | 852475-26-4 |
MW: | 314.3 D |
From 43.00€
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Item number: Cay16765-1
(+)-Cloprostenol is a synthetic analog of prostaglandin F2alpha (PGF2alpha). It is an FP receptor agonist and a potent luteolytic agent in rats and hamsters. (+)-Cloprostenol is the optically active, 15(R) enantiomer of cloprostenol responsible for the majority of its biological activity. It is 200 times more potent...
Keywords: | (+)-16-m-chlorophenoxy tetranor PGF2alpha, (+)-16-m-chlorophenoxy tetranor Prostaglandin F2alpha, D-Cloprostenol,... |
Application: | FP receptor agonist |
CAS | 54276-21-0 |
MW: | 424.9 D |
From 97.00€
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Item number: Cay16465-1
U-51605 is a stable analog of the endoperoxide prostaglandin H2 (PGH2). It is an inhibitor of both prostacyclin (PGI) and thromboxane (TX) synthases with more selectivity towards PGI synthase. U-51605 is also a partial agonist at TP receptors. In human foreskin fibroblasts, U-51605 inhibits PGI synthase at a...
Keywords: | 9alpha,11alpha-azoprosta-5Z,13E-dien-1-oic acid |
Application: | PGI synthase inhibitor |
CAS | 64192-56-9 |
MW: | 332.5 D |
From 58.00€
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Item number: Cay16645-1
4-Methylumbelliferyl Phosphate (4-MUP) is a fluorogenic substrate for phosphatases, including acid and alkaline phosphatases. It is converted to the fluorescent product 4-methylumbelliferone (4-MU), which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at...
Keywords: | 4-Methylumbelliferone Phosphate, 4-MU Phosphate, 4-MUP, 7-hydroxy-4-Methylcoumarin Phosphate,... |
Application: | Phosphatase fluorogenic substrate |
CAS | 3368-04-5 |
MW: | 256.2 D |
From 39.00€
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Item number: Cay16365-1
alpha-Hydroxyglutaric acid (2-HG, Cay-16374) is normally metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases. Mutations in these enzymes cause 2-hydroxyglutaric aciduria, a neurometabolic disorder. Recent studies have found that mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2,...
Keywords: | Octyl-2-HG, 2-hydroxy-pentanedioic acid, 1-octyl ester |
Application: | Cell-permeable 2-HG derivative |
CAS | 2097068-39-6 |
MW: | 260.3 D |
From 73.00€
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Item number: Cay16685-1
Lumula is a hybrid eicosanoid analog that incorporates the docosanoid and prostamide features of unoprostone (Cay-16680) and bimatoprost (17-phenyl trinor Prostaglandin F2alpha ethyl amide, Cay-16820), respectively, prostaglandin analogs that lack potency at the prostanoid FP receptor. Based on classical...
Keywords: | Maxeyprost, Unoprostone N-ethyl amide, N-ethyl-9alpha,11alpha-dihydroxy-15-oxo-20a,20b-dihomoprost-5-en-1-amide |
Application: | Bioactive lipid assays |
CAS | 511229-72-4 |
MW: | 409.6 D |
From 319.00€
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Item number: Cay16065-1
Arachidonoyl ethanolamide (AEA, Cay-90050), also known as anandamide, is an endogenous ligand of the cannabinoid receptors. AEA is metabolized by fatty acid amide hydrolase (FAAH) to give arachidonic acid (Cay-90010) and ethanolamine. ARN1203 is a fluorinated analog of AEA that serves as a substrate of FAAH (Km = 29...
Keywords: | N-(3-fluoro-2-hydroxypropyl)-5Z,8Z,11Z,14Z-eicosatetraenamide |
Application: | FAAH substrate |
CAS | 1428445-15-1 |
MW: | 379.6 D |
From 43.00€
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