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P1230-862
Anti-​Metabotropic Glutamate Receptor 7 (Ser862)
PhosphoSolutions
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100 µl

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419 €

Anti-Metabotropic Glutamate Receptor 7 (Ser862)


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Metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse (Bhattacharya et al., 2004, Francesconi et al., 2004, Wilson and Nicoll, 2001). The mGluRs are divided into three groups based on sequence identity and pharmacological properties: group I (mGluR1 and mGluR5) are localized in the perisynaptic region of the postsynaptic membrane, whereas group II (mGlur2 and mGluR3) and group III (mGluR4,6,7 and 8) are localized predominantly at presynaptic terminals. PKC phosphorylation of serine 862 on mGluR7 has been shown to be critical for stabilizing receptor surface expression and promoting binding to the synaptic PDZ-domain-containing protein PICK1 (Suh et al., 2008).

MW: 102 kD
Rabbit SR: rat, mouse, human, bovine, non-human primate, zebra fish, canine
Immunogen: synthetic phospho-peptide corresponding to amino acid residues surrounding phospho-Ser862 of rat mGluR7

UniProt ID: P35400
Image Art P1230-862 PhosphoSolutions Anti-​Metabotropic Glutamate Receptor 7 (Ser862)

- Geninformationen GeneID 81672

Weitere Produkte für dieses Protein:

Antibodies

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Products for: GRM6_7_8 - metabotropic glutamate receptor 6/7/8



Schlagworte:
Anti-​Grm7, Anti-​mGluR7, Anti-​Gprc1g, Anti-​Metabotropic glutamate receptor 7, antibody, antibodies, Antikörper

 

 

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