27 products were found matching "IHC-00575"!

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Anti-Menin (IHC)
Anti-Menin (IHC)

Item number: IHC-00572

Protein function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of...
Keywords: Anti-SCG2, Anti-MEN1, Anti-Menin
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
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Anti-PKD2 (IHC)
Anti-PKD2 (IHC)

Item number: IHC-00570

Protein function: Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of cell proliferation via MAPK1/3 (ERK1/2) signaling, oxidative stress- induced NF-kappa-B activation, inhibition of HDAC7...
Keywords: Anti-PKD2, Anti-PRKD2, Anti-HSPC187, Anti-nPKC-D2, EC=2.7.11.13, Anti-Serine/threonine-protein kinase D2
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Anti-Diaphanous 1 (IHC)
Anti-Diaphanous 1 (IHC)

Item number: IHC-00571

Protein function: Acts in a Rho-dependent manner to recruit PFY1 to the membrane. Required for the assembly of F-actin structures, such as actin cables and stress fibers. Nucleates actin filaments. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for...
Keywords: Anti-DRF1, Anti-DIAP1, Anti-DIAPH1, Anti-Diaphanous-related formin-1, Anti-Protein diaphanous homolog 1
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Anti-Leo1 (IHC)
Anti-Leo1 (IHC)

Item number: IHC-00573

Protein function: Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-...
Keywords: Anti-RDL, Anti-LEO1, Anti-RNA polymerase-associated protein LEO1, Anti-Replicative senescence down-regulated leo1-like...
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
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Anti-QKI (IHC)
Anti-QKI (IHC)

Item number: IHC-00574

Protein function: RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5'-NACUAAY-N(1,20)- UAAY-3' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to...
Keywords: Anti-QKI, Anti-Hqk, Anti-HKQ, Anti-HqkI, Anti-Protein quaking
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
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Anti-NF-YA IHC Antibody, affinity purifie (IHC)
Anti-NF-YA IHC Antibody, affinity purifie (IHC)

Item number: IHC-00576

Protein function: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'- CCAAT-3' box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively...
Keywords: Anti-NFYA, Anti-NF-YA, Anti-CAAT box DNA-binding protein subunit A, Anti-Nuclear transcription factor Y subunit A,...
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
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Anti-NF-YC (IHC)
Anti-NF-YC (IHC)

Item number: IHC-00577

Protein function: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'- CCAAT-3' box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors. [The UniProt Consortium]
Keywords: Anti-NFYC, Anti-NF-YC, Anti-Transactivator HSM-1/2, Anti-CAAT box DNA-binding protein subunit C, Anti-Nuclear...
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
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Anti-SAM68 (IHC)
Anti-SAM68 (IHC)

Item number: IHC-00578

Protein function: Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain- containing proteins. Role in G2-M progression in the cell...
Keywords: Anti-p68, Anti-Sam68, Anti-Src-associated in mitosis 68 kDa protein, Anti-GAP-associated tyrosine phosphoprotein p62,...
Application: IHC
Host: Rabbit
Species reactivity: human, mouse
From 164.00€ *
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Anti-eIF2A (IHC)
Anti-eIF2A (IHC)

Item number: IHC-00579

Protein function: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF- 2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon- dependent manner, whereas the eIF-2 complex...
Keywords: Anti-CDA02, Anti-EIF2A
Application: IHC
Host: Rabbit
Species reactivity: human
From 164.00€ *
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Anti-PTEN
Anti-PTEN

Item number: 030575.100

PTEN (phosphatase and tensin homolog) was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. This protein is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity...
Keywords: Anti-PTEN, Anti-MMAC1, EC=3.1.3.67, EC=3.1.3.48, EC=3.1.3.16, Anti-Phosphatase and tensin homolog, Anti-Mutated in...
Application: ELISA, FC, ICC, IF, WB
Host: Mouse
Species reactivity: human, mouse
682.00€ *
Review
Anti-Ki-67 (IHC)
Anti-Ki-67 (IHC)

Item number: IHC-00375

Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226)....
Keywords: Anti-Antigen Ki67 homolog, Anti-Antigen KI-67 homolog, Anti-Proliferation marker protein Ki-67, Anti-Antigen identified by...
Application: IHC
Host: Rabbit
Species reactivity: mouse
From 164.00€ *
Review
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Anti-Caspase-8 (human), clone C15
Anti-Caspase-8 (human), clone C15

Item number: AG-20B-0057-C100

Recognizes the p18 subunit of human caspase-8. Liquid. Purified from concentrated hybridoma tissue culture supernatant. Procaspase-8 belongs to the family of caspases. Binding of FasL to Fas leads to formation of a receptor complex at the cellular membrane, which was named DISC. The DISC consists of oligomerized...
Keywords: Anti-Casp-8, Anti-CAP4, Anti-FADD-like ICE, EC=3.4.22.61
Application: ICC, IP, WB
Host: mouse
Species reactivity: human
264.00€ * From 237.60€ *
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