Anti-LSD1 (aa 450-500)

Anti-LSD1 (aa 450-500)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13486-1 1 each -

6 - 10 business days*

413.00€
 
LSD1, the first known lysine-specific histone demethylase, is an 886 amino acid nuclear protein... more
Product information "Anti-LSD1 (aa 450-500)"
LSD1, the first known lysine-specific histone demethylase, is an 886 amino acid nuclear protein belonging to flavin monoamine oxidase family. It contains a SWIRM domain, a FAD-binding motif and an amine oxidase domaine. This protein is ubiquitously expressed and is a component of several histone deacetylase complexes. LSD1 acts as a component of the CoREST and other transcriptional co-repressor complexes and also plays an important role in silencing neuronal-specific genes in non-neuronal cells. It is also known to demethylate Lys4 of histone H3, a specific tag for epigenetic transcriptional activation. Reports suggest that it plays an important role in stimulating androgen-receptor-dependent transcription converting oxygen to hydrogen peroxide (might use alternative electron acceptors). Along with nuclear FHL2 it serves as a novel biomarker predictive for prostate cancer.Synonyms: KDM1. Immunogen: synthetic peptide from human LSD1 amino acids 450-500. Formulation: (Request formulation change), 100 µg of protein A-purified IgG. Storage Buffer: 200 µl PBS with 0.05% BSA and 0.05% sodium azide. Host: Rabbit. Applications: WB. Origin: Animal/Rabbit.
Keywords: KDM1
Supplier: Cayman Chemical
Supplier-Nr: 13486

Properties

Application: WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: synthetic peptide from human LSD1 amino acids 450-500
Format: Purified

Database Information

KEGG ID : K11450 | Matching products
UniProt ID : O60341 | Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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